A client with rheumatoid arthritis and psoriasis has been prescribed adalimumab, a biologic agent that blocks tumor necrosis factor alpha (TNF-alpha). Which of the following statements by the client indicates a need for further teaching?

Choice A reason: Oily stools are common, especially when excessive fat is consumed, because orlistat blocks the absorption of fat in the intestines. The undigested fat is then eliminated in the stool, making it oily, greasy, or foul-smelling.

Choice B reason: Many patients note having an increase of gas and flatus, because orlistat can also interfere with the digestion of carbohydrates and proteins, causing fermentation and gas production in the colon.

Choice C reason: Constipation is not a common side effect with this medication. In fact, orlistat may cause the opposite effect of diarrhea, as the unabsorbed fat can irritate the bowel and increase the motility.

Choice D reason: Some patients report the development of fecal incontinence, because orlistat can cause unpredictable bowel movements and difficulty in controlling the passage of stool, especially if the patient consumes a high-fat diet.

Choice E reason: This medication does have side effects, even though it can be bought over the counter. Orlistat is a prescription-strength drug that can cause serious adverse reactions, such as liver damage, kidney stones, gallbladder problems, and vitamin deficiencies. The over-the-counter version is a lower dose than the prescription one, but it still requires medical supervision and lifestyle changes.

Choice A reason: Normal saline is not contraindicated for a dehydrated client with a skull fracture. Normal saline is an isotonic solution that has the same concentration of solutes as the blood plasma. It can help restore fluid balance and prevent cerebral edema.

Choice B reason: Dextrose in water 5% is contraindicated for a dehydrated client with a skull fracture. Dextrose in water 5% is a hypotonic solution that has a lower concentration of solutes than the blood plasma. It can cause fluid to shift from the blood vessels into the brain cells, increasing the intracranial pressure and worsening the skull fracture.

Choice C reason: Lactated Ringer's (LR) is not contraindicated for a dehydrated client with a skull fracture. Lactated Ringer's (LR) is an isotonic solution that has the same concentration of solutes as the blood plasma. It can also provide electrolytes such as sodium, potassium, calcium, and lactate, which can help correct acid-base imbalances.

Choice D reason: Dextrose in normal saline is not contraindicated for a dehydrated client with a skull fracture. Dextrose in normal saline is a hypertonic solution that has a higher concentration of solutes than the blood plasma. It can cause fluid to shift from the brain cells into the blood vessels, reducing the intracranial pressure and cerebral edema.