A client with peptic ulcer disease is prescribed a combination therapy that includes antibiotics and acid-reducing medications. The client asks the nurse about the purpose of the antibiotics in the treatment. Which of the following responses should the nurse provide?

Choice A reason:

Taking sucralfate with meals is not recommended, as it can reduce its effectiveness. Sucralfate should be taken on an empty stomach, at least 1 hour before meals, to allow it to form a protective barrier over the ulcerated areas.

Choice B reason:

Crushing sucralfate tablets is not advised, as it can interfere with the medication's ability to adhere to the ulcer site and provide protection.

Choice C reason:

This statement is correct. Taking antacids with sucralfate can reduce its effectiveness, as antacids can interfere with its therapeutic actions. Clients should avoid taking antacids together with sucralfate.

Choice D reason:

Sucralfate does not typically cause drowsiness, so taking it before bedtime is not necessary for this medication. It should be taken at regular intervals during the day as prescribed.

Choice A reason:

Antibiotics do not directly heal the ulcer or reduce stomach acid production. They are prescribed specifically to treat Helicobacter pylori (H. pylori) infection, a common cause of peptic ulcers.

Choice B reason:

This statement is correct. Antibiotics are prescribed to treat H. pylori infection, which is a major cause of peptic ulcers. By eliminating the bacterial infection, the ulcer has a better chance of healing and preventing recurrence.

Choice C reason:

Antibiotics do not promote blood clotting or reduce the risk of bleeding from the ulcer. Other medications may be prescribed to manage bleeding if it occurs.

Choice D reason:

Antibiotics do not relax stomach muscles or alleviate abdominal pain. Pain relief is typically achieved through acid-reducing medications and other pain management strategies.