A client with immune thrombocytopenic purpura (ITP) will begin treatment with romiplostim (Nplate) to be administered by subcutaneous injection in the provider's office once per week. Which statement should the nurse plan to include when educating the client about this medication?
This medication increases the production of plasma enzyme ADAMTS-13.
This medication prevents platelets from being destroyed in the spleen.
This medication prevents platelets from binding with heparin.
This medication stimulates the bone marrow to increase platelet production.
The Correct Answer is D
A. Romiplostim does not increase the production of ADAMTS-13; it is used to increase platelet counts.
B. Romiplostim does not prevent platelet destruction in the spleen; it works by stimulating platelet production.
C. Romiplostim does not prevent platelets from binding with heparin; it is not used for heparin-induced thrombocytopenia.
D. Romiplostim is a thrombopoietin receptor agonist that stimulates the bone marrow to increase platelet production, which is its primary mechanism of action in treating ITP.
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Related Questions
Correct Answer is C
Explanation
A. Pleural effusion may be a complication of heart failure but does not directly explain the decreased urine output and elevated serum creatinine.
B. Myocardial infarction would present with different symptoms, such as chest pain, rather than decreased urine output and elevated creatinine.
C. Cardiorenal syndrome refers to the interdependence of the heart and kidneys, where chronic heart failure leads to worsening kidney function, causing symptoms like decreased urine output and elevated serum creatinine.
D. Heparin-induced thrombocytopenia (HIT) is related to the use of heparin and presents with low platelet counts, not decreased urine output and elevated creatinine.
Correct Answer is D
Explanation
A. Vitamin K is an antidote for warfarin, not heparin.
B. Enoxaparin is a low molecular weight heparin and is contraindicated in patients with a history of HIT.
C. Warfarin is an oral anticoagulant used for long-term anticoagulation therapy and is not used to neutralize heparin.
D. Protamine sulfate is the specific antidote for heparin and is used to neutralize its effects.
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