A client with immune thrombocytopenic purpura (ITP) will begin treatment with romiplostim (Nplate) to be administered by subcutaneous injection in the provider's office once per week. Which statement should the nurse plan to include when educating the client about this medication?
This medication increases the production of plasma enzyme ADAMTS-13.
This medication prevents platelets from being destroyed in the spleen.
This medication prevents platelets from binding with heparin.
This medication stimulates the bone marrow to increase platelet production.
The Correct Answer is D
A. Romiplostim does not increase the production of ADAMTS-13; it is used to increase platelet counts.
B. Romiplostim does not prevent platelet destruction in the spleen; it works by stimulating platelet production.
C. Romiplostim does not prevent platelets from binding with heparin; it is not used for heparin-induced thrombocytopenia.
D. Romiplostim is a thrombopoietin receptor agonist that stimulates the bone marrow to increase platelet production, which is its primary mechanism of action in treating ITP.
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Related Questions
Correct Answer is B
Explanation
A. Plasmapheresis in TTP aims to remove abnormal blood components, not ADAMTS-13. In fact, plasmapheresis helps replenish ADAMTS-13.
B. The primary goal of plasmapheresis in TTP is to remove large von Willebrand factor molecules that are causing platelet aggregation and clot formation.
C. Removing macrophages from the spleen is not the objective of plasmapheresis.
D. Plasmapheresis is usually performed daily until clinical and laboratory parameters improve, not just once a week.
Correct Answer is C
Explanation
A. Elevated BUN can indicate kidney dysfunction but is not specific for assessing heart failure severity.
B. Elevated troponin levels indicate myocardial injury or infarction, not heart failure exacerbation.
C. B-type natriuretic peptide (BNP) levels are directly correlated with the severity of heart failure, as they are released in response to ventricular volume expansion and pressure overload.
D. An electrocardiogram (ECG) can show arrhythmias or ischemia but does not directly measure heart failure severity.
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