A client with acquired immune deficiency syndrome (AIDS) and Pneumocystis jiroveci pneumonia has a CD4+ T cell count of 200 cells/mm³ (20%). The client asks the nurse why they have these recurring massive infections. Which pathophysiologic mechanism should the nurse describe in response to this client's question?
Reference Range:
T-helper CD4 cells [600 to 1500 cells/mm³ (60 to 75%)]
The humoral immune response lacks B cells that form antibodies and opportunistic infections result.
Inadequate numbers of T lymphocytes are available to initiate cellular immunity and macrophages.
Bone marrow suppression of white blood cells causes insufficient cells to phagocytize organisms.
Exposure to multiple environmental infectious agents overburdens the immune system until it fails.
The Correct Answer is B
Choice A reason: This is incorrect because the humoral immune response involves B cells that produce antibodies against specific antigens. However, AIDS affects the cellular immune response, which involves T cells that activate other immune cells and directly kill infected cells.
Choice B reason: This is correct because AIDS is caused by human immunodeficiency virus (HIV), which infects and destroys CD4+ T cells, also known as helper T cells. These cells are essential for initiating and regulating both humoral and cellular immunity. Without enough CD4+ T cells, the body cannot mount an effective response against pathogens, especially opportunistic infections that take advantage of a weakened immune system.
Choice C reason: This is incorrect because bone marrow suppression of white blood cells is not a direct consequence of AIDS. However, some drugs used to treat AIDS, such as zidovudine, may cause bone marrow suppression as a side effect.
Choice D reason: This is incorrect because exposure to multiple environmental infectious agents does not cause AIDS. However, people with AIDS are more susceptible to infections from various sources due to their impaired immune system.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A reason: Applying prescribed lotions to the radiation site is a good action for a client with cancer receiving external beam radiation, because it can help moisturize and protect the skin from irritation and breakdown. The client should follow the instructions of the health care provider regarding the type and frequency of lotion application. Therefore, this choice does not indicate a need for further teaching.
Choice B reason: Washing the radiation site with antibacterial soap and water is a bad action for a client with cancer receiving external beam radiation, because it can cause dryness, inflammation, and infection of the skin. The client should use mild soap and water or saline solution to gently cleanse the area without rubbing or scrubbing. Therefore, this choice indicates a need for further teaching.
Choice C reason: Wearing clothing to cover the radiation site is a good action for a client with cancer receiving external beam radiation, because it can help shield the skin from sun exposure and friction. The client should wear loose-fitting, soft, cotton clothing that does not irritate or constrict the area. Therefore, this choice does not indicate a need for further teaching.
Choice D reason: Drying the area with patting motions after taking a shower is a good action for a client with cancer receiving external beam radiation, because it can help prevent trauma and infection of the skin. The client should avoid rubbing or scratching the area or using hair dryers or heating pads on it. Therefore, this choice does not indicate a need for further teaching.
Correct Answer is D
Explanation
Choice A reason: Canned vegetables with additional table salt are not a good choice for someone with cholecystitis, because they are high in sodium, which can increase fluid retention and inflammation. However, this choice is not eliminated by the client, so it does not indicate successful teaching.
Choice B reason: Pasta with herbal butter and no meat sauce is a good choice for someone with cholecystitis, because it is low in fat and protein, which can trigger gallbladder contractions and pain. This choice is not eliminated by the client, so it does not indicate successful teaching.
Choice C reason: Citrus fruit and melon with a salt substitute are also good choices for someone with cholecystitis, because they are high in vitamin C and water, which can help dissolve gallstones and prevent infection. This choice is not eliminated by the client, so it does not indicate successful teaching.
Choice D reason: Whole milk and daily servings of ice cream are bad choices for someone with cholecystitis, because they are high in fat and cholesterol, which can worsen gallbladder inflammation and increase the risk of gallstone formation. This choice is eliminated by the client, so it indicates successful teaching.
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