A client with a history of atrial fibrillation is prescribed warfarin. Which laboratory value should the nurse monitor to assess the medication’s effectiveness?

Choice A reason: Palpating for joint warmth and swelling is the best technique for early rheumatoid arthritis, as it detects synovitis, a hallmark of the disease. Inflamed joints are warm, swollen, and tender due to autoimmune-driven synovial proliferation, enabling early identification and intervention to prevent joint damage.

Choice B reason: Measuring range of motion assesses joint function but is less specific for early rheumatoid arthritis. Reduced motion occurs later, after significant synovial inflammation or damage. Palpating for warmth and swelling directly identifies active synovitis, making it more effective for early detection.

Choice C reason: Assessing grip strength evaluates muscle and joint function but is nonspecific for early rheumatoid arthritis. Weakness may result from pain or later joint damage. Palpating for warmth and swelling targets synovial inflammation, the earliest sign, making it the preferred technique for early diagnosis.

Choice D reason: Observing gait and posture detects functional limitations but is not specific for early rheumatoid arthritis. Gait changes occur with advanced disease or other conditions. Palpating for joint warmth and swelling directly identifies synovial inflammation, the primary early feature, making it more diagnostic.

Choice A reason: Neutropenia, a low neutrophil count, is a common chemotherapy side effect due to bone marrow suppression, increasing infection risk. Monitoring neutrophil counts is critical, as infections in breast cancer patients can be life-threatening, making it the priority side effect to assess.

Choice B reason: Hypertension is not a typical chemotherapy side effect, though some agents cause cardiovascular effects. Neutropenia is more common, compromising immunity, making it the priority to monitor, as infections pose an immediate threat in breast cancer patients on chemotherapy.

Choice C reason: Hyperkalemia is rare with chemotherapy, except in tumor lysis syndrome. Neutropenia is a frequent side effect, increasing infection risk due to marrow suppression, making it the priority to monitor, as it directly impacts patient safety during breast cancer treatment.

Choice D reason: Weight gain is not a primary chemotherapy side effect; weight loss is more common due to nausea. Neutropenia is critical to monitor, as low neutrophils increase infection risk, requiring urgent intervention in breast cancer patients undergoing chemotherapy.