A client receives a prescription for itraconazole. Which information provided by the client requires additional instruction by the nurse?
Report any difficulty with breathing.
Monitor for changes in stool color.
Avoid the consumption of grapefruit juice.
Take the medication with antacids.
The Correct Answer is D
Itraconazole is an antifungal medication used to treat a variety of fungal infections. Antacids, which are used to treat heartburn and acid reflux, can decrease the absorption of itraconazole in the body. Therefore, it is important to instruct the client to avoid taking itraconazole with antacids. If the client needs to take an antacid, it should be taken at least 2 hours before or after taking itraconazole.
Reporting any difficulty with breathing is important as it can be a sign of an allergic reaction to the medication. Monitoring for changes in stool color is important as it can be an indication of liver dysfunction, which is a potential side effect of itraconazole.
Avoiding the consumption of grapefruit juice is important as it can increase the level of itraconazole in the body, which can increase the risk of side effects.
In summary, the client should be instructed to avoid taking itraconazole with antacids and to take any antacid at least 2 hours before or after taking itraconazole. The client should also be instructed to report any difficulty with breathing and to monitor for changes in stool color. Additionally, the client should avoid consuming grapefruit juice while taking itraconazole.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
The correct answer is Choice D
Choice A rationale: Splinting with a pillow may reduce discomfort during movement or coughing by stabilizing the incision site, but it does not address acute postoperative pain with sympathetic overdrive. The elevated heart rate, respiratory rate, and blood pressure suggest a stress response mediated by catecholamines. Without analgesia, nociceptive signals continue to activate the hypothalamic-pituitary-adrenal axis. While splinting is supportive, it lacks the pharmacologic efficacy needed to blunt nociceptive transmission at the spinal or supraspinal level.
Choice B rationale: Assessing IV patency is a procedural prerequisite for medication administration but not a therapeutic intervention in itself. It does not directly address the pathophysiology of acute pain or the sympathetic surge evidenced by tachycardia and hypertension. Pain activates ascending pathways via A-delta and C fibers, requiring pharmacologic blockade. IV access assessment is necessary but secondary to the urgent need for analgesia to prevent complications like hypoxia, hyperventilation, or delayed recovery.
Choice C rationale: High Fowler positioning may improve diaphragmatic excursion and reduce pulmonary complications, but it does not mitigate visceral or incisional pain. In fact, increased intra-abdominal pressure from upright posture may exacerbate pain at the surgical site. Pain perception involves central sensitization and peripheral nociceptor activation, which are unaffected by positioning. The client’s pale skin and elevated vitals indicate systemic distress requiring analgesic intervention, not postural adjustment. Thus, this choice lacks direct analgesic benefit.
Choice D rationale: IV analgesics act rapidly to inhibit nociceptive transmission at the spinal cord and brainstem levels. Opioids bind to mu receptors, reducing neurotransmitter release and hyperpolarizing neurons, thereby dampening pain signals. This intervention directly targets the physiologic cause of elevated heart rate, respiratory rate, and blood pressure. Normal heart rate is 60–100 bpm, respiratory rate 12–20 breaths/min, and BP <120/80 mmHg. Prompt analgesia prevents complications like hypoxia, delayed healing, and neuroendocrine stress
Correct Answer is B
Explanation
A) Incorrect- Genetically inherited disorders of family members: While a family history of certain disorders might provide some insight, it is not typically the primary cause of elevated serum magnesium levels in an older adult.
B) Correct- Elevated serum magnesium levels are commonly associated with chronic laxative use, especially those containing magnesium-based compounds. Laxatives can lead to excessive magnesium intake, causing hypermagnesemia.
C. Incorrect- Smoking is not a common cause of elevated serum magnesium levels.
D. Incorrect- While dietary sources can contribute to magnesium intake, chronic laxative use is a more likely cause in this context.
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