A client ordered grapefruit juice for breakfast. The nurse should review the client's medication record for medications metabolized by the:
Gall bladder
Liver
Kidney
Small bowel
The Correct Answer is B
B. Liver: Grapefruit juice inhibits CYP3A4 enzymes in the liver, which metabolize many drugs (e.g., statins, calcium channel blockers). This inhibition can lead to increased drug levels and toxicity.
A. Gall bladder – The gall bladder stores bile but does not metabolize drugs.
C. Kidney – The kidneys excrete drugs, but grapefruit juice does not significantly impact renal metabolism.
D. Small bowel – Some drug metabolism occurs in the intestines, but grapefruit juice primarily affects liver enzymes.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. "Most allergic responses include hives or a rash.": Allergic reactions often present with hives (urticaria), rash, itching, and sometimes anaphylaxis. Severe reactions can cause airway swelling, difficulty breathing, and hypotension.
B. "Common allergic reactions may include fever and diarrhea." Fever and diarrhea are more typical of infections, not allergic reactions.
C. "You might feel cold and sweaty if you are having an allergic reaction." Cold, clammy skin may indicate shock, but it is not specific to allergies.
D. "Nausea and vomiting usually mean you are allergic to the medication." GI symptoms may indicate intolerance but not necessarily an allergy.
Correct Answer is D
Explanation
A. Neuroleptic malignant syndrome: Causes fever, muscle rigidity, autonomic instability, and altered mental status-not dry mouth or blurry vision.
B. Teratogenicity: Refers to birth defects from medications taken during pregnancy.
C. Parkinson-like syndrome: Involves tremors, muscle rigidity, and bradykinesia-not dry mouth or blurry vision.
D. Anticholinergic effects: Symptoms of dry mouth, blurred vision, and urinary retention are classic signs of anticholinergic side effects caused by medications like antihistamines, tricyclic antidepressants, and some antipsychotics.
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