A 52-year-old female presents with continuous abdominal pain that intensifies after eating. She is diagnosed with chronic pancreatitis. Contributing factors include:
alcohol abuse
bulimia
history of gallstones
bacterial infection
Correct Answer : A,C
Choice A reason:
Alcohol abuse is the leading cause of chronic pancreatitis in many cases. Chronic alcohol consumption leads to repeated episodes of pancreatic inflammation, resulting in fibrosis, loss of pancreatic function, and structural damage. Alcohol directly stimulates pancreatic secretions and contributes to the formation of protein plugs that obstruct pancreatic ducts, exacerbating the condition.
Choice B reason:
Bulimia is not a known contributing factor for chronic pancreatitis. While eating disorders can have gastrointestinal manifestations, they do not directly lead to the chronic inflammatory process seen in pancreatitis.
Choice C reason:
A history of gallstones is a recognized contributing factor to chronic pancreatitis. Gallstones can intermittently block the pancreatic duct, leading to inflammation and damage over time. While gallstones are more commonly associated with acute pancreatitis, they also play a role in the chronic form if untreated or recurrent.
Choice D reason:
Bacterial infection is not a primary contributing factor to chronic pancreatitis. While infections can complicate pancreatic conditions, they do not typically initiate the chronic inflammatory process. Chronic pancreatitis is more often caused by mechanical, toxic, or genetic factors rather than infectious agents.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A reason:
Pulmonary embolism is not a typical complication of a peptic ulcer. While serious, pulmonary embolism is unrelated to the gastrointestinal tract and would not arise from ulceration of the stomach or duodenum. It is therefore not the correct answer to the question posed.
Choice B reason:
Bleeding is the primary clinical manifestation of greatest concern with a peptic ulcer. Ulcers can erode into blood vessels, leading to gastrointestinal hemorrhage, which may present as hematemesis (vomiting blood) or melena (black, tarry stools). Severe bleeding can result in hypovolemic shock and requires immediate medical intervention, such as endoscopic hemostasis, blood transfusions, or surgery. This makes bleeding the most critical concern among the options listed.
Choice C reason:
Bowel obstruction can occur as a complication of peptic ulcer disease but is less common compared to bleeding. It arises from scarring or swelling near the pylorus, leading to gastric outlet obstruction. While serious, it is not the most frequent or immediate concern in the context of peptic ulcers.
Choice D reason:
Hepatomegaly, or enlargement of the liver, is unrelated to peptic ulcer disease. This symptom is typically associated with liver conditions such as cirrhosis, hepatitis, or cancer, and does not result from ulcer pathology.
Correct Answer is A
Explanation
Choice A reason:
Using a different antifungal agent might be necessary due to the potential interaction between voriconazole and warfarin. Voriconazole can increase the anticoagulant effects of warfarin, leading to an increased risk of bleeding. Therefore, selecting an alternative antifungal that does not interact with warfarin could be the safest option for the patient.
Choice B reason:
Reducing the dose of voriconazole may not adequately address the drug interaction issue. Voriconazole can significantly affect warfarin metabolism even at lower doses, leading to potential complications. Therefore, this choice is less likely to be recommended.
Choice C reason:
Administering intravenous voriconazole does not change its interaction with warfarin. The method of administration does not alter the drug's effect on warfarin metabolism, making this option inappropriate for managing the drug interaction.
Choice D reason:
Increasing the dose of warfarin is not a viable option as voriconazole increases warfarin's anticoagulant effect. This would further elevate the risk of bleeding and is not recommended. Thus, this option is incorrect.
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