A 45-year-old female patient presents with symptoms of tingling in the fingers, muscle cramps, and fatigue. Her laboratory results show low serum calcium, low parathyroid hormone (PTH) levels, and elevated serum phosphate levels. Based on these lab results, which of the following is the most likely diagnosis?
Primary hyperparathyroidism
Chronic kidney disease
Vitamin D deficiency
Hypoparathyroidism
The Correct Answer is D
Choice A Reason:
Primary hyperparathyroidism is characterized by elevated PTH levels, which lead to increased serum calcium levels and decreased serum phosphate levels. The patient’s lab results show low PTH and low serum calcium, which are not consistent with primary hyperparathyroidism.
Choice B Reason:
Chronic kidney disease (CKD) can cause disturbances in calcium and phosphate metabolism, but it typically presents with elevated PTH levels due to secondary hyperparathyroidism. The patient’s low PTH levels make CKD an unlikely diagnosis in this context.
Choice C Reason:
Vitamin D deficiency can lead to low serum calcium levels, but it usually results in elevated PTH levels as the body attempts to compensate for the low calcium. The patient’s low PTH levels do not align with a diagnosis of vitamin D deficiency.
Choice D Reason:
Hypoparathyroidism is characterized by low serum calcium, low PTH levels, and elevated serum phosphate levels. This condition occurs when the parathyroid glands do not produce enough PTH, leading to the observed lab results and symptoms such as tingling, muscle cramps, and fatigue. The patient’s lab results are consistent with hypoparathyroidism.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A Reason:
Administering propranolol intravenously is the most appropriate initial intervention for managing a thyroid storm. Thyroid storm is a life-threatening condition characterized by severe hyperthyroidism, leading to symptoms such as tachycardia, hypertension, and hyperthermia. Propranolol, a non-selective beta-blocker, helps control these symptoms by reducing heart rate and blood pressure. Additionally, propranolol inhibits the peripheral conversion of T4 to T3, the more active form of thyroid hormone, thereby reducing the overall thyroid hormone activity. This makes it a critical first step in stabilizing the patient.
Choice B Reason:
Administering dextrose 50% intravenously is not the most appropriate initial intervention for thyroid storm. Dextrose 50% is typically used to treat severe hypoglycemia by rapidly increasing blood glucose levels. While maintaining adequate glucose levels is important, it does not address the primary issue of excessive thyroid hormone activity in thyroid storm.
Choice C Reason:
Administering levothyroxine orally is inappropriate in the context of thyroid storm. Levothyroxine is a synthetic form of T4 used to treat hypothyroidism, not hyperthyroidism. Administering it in a thyroid storm would exacerbate the condition by increasing the levels of thyroid hormone in the body.
Choice D Reason:
Administering insulin to control hyperglycemia is not the primary intervention for thyroid storm. While hyperglycemia can occur in thyroid storm due to increased metabolic activity, the immediate priority is to control the excessive thyroid hormone activity. Insulin administration would be secondary to stabilizing the patient’s thyroid function.
Correct Answer is D
Explanation
Choice A Reason:
Diabetes Insipidus (DI) is characterized by excessive urination and thirst due to a deficiency of antidiuretic hormone (ADH) or a renal insensitivity to ADH. Patients with DI typically present with hypernatremia (high serum sodium) and low urine osmolality, which contrasts with the findings of low serum sodium and high urine osmolality in this patient.
Choice B Reason:
Adrenal insufficiency can cause hyponatremia and hyperkalemia due to a deficiency in aldosterone and cortisol. However, it usually presents with low serum osmolality and low urine sodium, which does not align with the patient’s laboratory results of high urine osmolality and elevated urine sodium.
Choice C Reason:
Hyperaldosteronism leads to increased sodium reabsorption and potassium excretion, resulting in hypernatremia and hypokalemia. This condition does not match the patient’s findings of hyponatremia and high urine osmolality.
Choice D Reason:
Syndrome of inappropriate Antidiuretic Hormone (SIADH) is characterized by excessive release of ADH, leading to water retention, hyponatremia, and concentrated urine. The patient’s laboratory results of low serum sodium, low serum osmolality, high urine osmolality, and elevated urine sodium are consistent with SIADH. This condition causes the kidneys to reabsorb water, diluting the blood and concentrating the urine.
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