Which of the following is an advantage of rectal drug administration?
It is useful for patients who are unable to take medications orally
It can reduce systemic side effects
It bypasses first-pass metabolism
All of the above
The Correct Answer is D
Rectal drug administration is useful for patients who are unable to take medications orally due to nausea, vomiting, or difficulty swallowing. This route of administration can reduce systemic side effects by delivering drugs directly to the rectum and lower colon. Rectal drug administration also bypasses first-pass metabolism in the liver.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Acetaminophen is commonly administered rectally in the form of a suppository for the treatment of pain and fever. This route of administration allows for effective delivery of medication in patients who are unable to take medications orally.
b. Furosemide is commonly administered orally or intravenously, not rectally.
c. Metoprolol is commonly administered orally, not rectally.
d. Simvastatin is commonly administered orally, not rectally.
Correct Answer is D
Explanation
Rectal pH, the presence of stool in the rectum and blood flow to the rectum can all affect absorption of rectally administered drugs. For example, some drugs may require an acidic environment for optimal absorption and may be affected by changes in rectal pH. The presence of stool in the rectum can also affect absorption by altering contact between the drug and mucous membranes. Blood flow to the rectum can affect absorption by altering the rate at which drugs are delivered to the absorption site.
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