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Which of the following immune system components plays a key role in the etiology of psoriasis?

A.

T-cells

B.

B-cells

C.

Platelets

D.

Eosinophils

Answer and Explanation

The Correct Answer is A

Explanation: Psoriasis is an autoimmune disorder in which T-cells, a type of white blood cell, become overactive and trigger an inflammatory response. These T-cells promote the rapid growth of skin cells, leading to the characteristic plaques seen in psoriasis.

Incorrect choices: b. B-cells: While B-cells are important components of the immune system, they are not primarily involved in the etiology of psoriasis. T-cells are the central players in the autoimmune response seen in psoriasis.

c. Platelets: Platelets are primarily responsible for blood clotting and are not directly related to the development of psoriasis.

d. Eosinophils: Eosinophils are a type of white blood cell involved in immune responses against parasitic infections and allergic reactions. While they are important in certain immune processes, they are not the main players in psoriasis etiology.


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Related Questions

Correct Answer is A

Explanation

Explanation: Psoriasis has a strong genetic component, and individuals with a family history of the condition are more likely to develop it. Specific genetic factors are involved in the immune response and skin cell growth regulation, leading to psoriasis.

Incorrect choices: b. While exposure to certain chemicals and irritants can exacerbate psoriasis symptoms, they are not the primary factor contributing to its development.

c. Psoriasis is not caused by a bacterial infection. It is a non-infectious inflammatory skin disorder.

d. Sun exposure can affect psoriasis, but it is not the primary factor contributing to its development. In some cases, moderate sunlight exposure may even improve psoriasis symptoms.

Correct Answer is D

Explanation

Explanation: Auspitz sign is a characteristic finding in psoriasis where pinpoint bleeding occurs when scales on the skin are removed. It is caused by the rapid growth and shedding of skin cells, which leads to the formation of delicate blood vessels that bleed easily.

Incorrect choices: a. Auspitz sign is not related to increased bleeding tendency in the patient; it is specific to psoriasis and its characteristic skin changes.

b. Presence of skin pustules and blisters is not associated with Auspitz sign and may indicate other skin conditions.

c. Formation of deep fissures in the skin is not directly related to Auspitz sign, which focuses on the bleeding after scale removal.

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