Which medication works by inhibiting the sodium-glucose cotransporter 2 (SGLT2) in the kidneys, leading to increased glucose excretion in the urine, and is used in the treatment of type 2 diabetes mellitus?
Metformin.
Glipizide.
Empagliflozin.
Insulin detemir.
The Correct Answer is C
Empagliflozin is an SGLT2 inhibitor that reduces renal glucose reabsorption, leading to increased urinary glucose excretion and improved glycemic control in type 2 diabetes mellitus.
Incorrect choices:
a. This choice is incorrect. Metformin primarily improves insulin sensitivity and reduces hepatic glucose production.
b. This choice is incorrect. Glipizide stimulates insulin secretion from pancreatic beta cells.
d. This choice is incorrect. Insulin detemir is a long-acting basal insulin used in insulin therapy.
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Related Questions
Correct Answer is B
Explanation
The "three P's" of diabetes mellitus refer to polyuria (excessive urination), polydipsia (excessive thirst), and polyphagia (excessive hunger) due to the body's inability to effectively use glucose for energy.
Incorrect choices:
a. This choice is incorrect. Increased appetite, weight gain, and bloating are not characteristic of diabetes mellitus; rather, diabetes is associated with weight loss despite increased appetite (polyphagia).
c. This choice is incorrect. Pallor, palpitations, and pain are not specific manifestations of diabetes mellitus.
d. This choice is incorrect. Panic attacks, paranoia, and paresthesia are not typical clinical manifestations of diabetes mellitus.
Correct Answer is C
Explanation
The OGTT involves drinking a glucose solution and measuring blood glucose levels at specific intervals. It is used to assess glucose tolerance and diagnose gestational diabetes mellitus during pregnancy.
Incorrect choices:
a. This choice is incorrect. The fasting blood glucose test measures blood glucose levels after an overnight fast and is not specifically used for diagnosing gestational diabetes.
b. This choice is incorrect. The HbA1c test measures average blood glucose levels over the past 2-3 months and is not typically used for diagnosing gestational diabetes.
d. This choice is incorrect. The random blood glucose test measures blood glucose levels at any time and is not specific for diagnosing gestational diabetes.
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