When researching information about a drug, the nurse finds that the drug tightly binds to protein. The nurse would interpret this to mean that the drug will:
be released fairly quickly.
have a long duration of action.
be excreted quickly.
lead to toxicity when given.
The Correct Answer is B
A. A drug that binds tightly to protein is typically released slowly, not quickly, as it remains bound in circulation.
B. Tight binding to proteins usually results in a prolonged duration of action since the drug is released gradually into the bloodstream, leading to sustained therapeutic effects.
C. Drugs that bind tightly to protein are generally not excreted quickly; they remain in circulation longer due to the binding.
D. While toxicity can occur with any drug, tight protein binding does not inherently lead to toxicity; it primarily affects the pharmacokinetics of the drug.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A. Prothrombin time (PT) is used to monitor warfarin therapy, not heparin therapy.
B. Activated partial thromboplastin time (aPTT) is the primary laboratory test used to assess the effectiveness of heparin therapy, measuring the time it takes for blood to clot and ensuring therapeutic levels.
C. The International normalized ratio (INR) is also related to warfarin therapy rather than heparin.
D. Serum potassium level is not relevant for assessing heparin therapy but may be monitored for other reasons.
Correct Answer is D
Explanation
A. Sodium levels are important to monitor, but they are not the primary concern with furosemide treatment.
B. Bone marrow function is not a direct concern related to furosemide therapy.
C. Calcium levels are less critical compared to potassium when monitoring a client on furosemide.
D. Potassium levels are correct because furosemide is a loop diuretic that can lead to significant potassium loss, putting the client at risk for hypokalemia, which can have serious cardiac implications.
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