When involved in phase III drug evaluation studies, what responsibilities would the nurse have?
Working with animals who are given experimental drugs.
Conducting research to determine the effectiveness of the drug.
Monitoring and observing patients closely for adverse effects.
Choosing appropriate patients to be involved in the study.
The Correct Answer is C
Choice A rationale
Working with animals is typically done in preclinical trials before phase I studies in humans and is not part of phase III drug evaluation studies.
Choice B rationale
Conducting research to determine the effectiveness of the drug is part of phase II studies. Phase III studies focus more on confirming effectiveness, monitoring side effects, and comparing it to commonly used treatments.
Choice C rationale
Monitoring and observing patients closely for adverse effects is a key responsibility in phase III drug evaluation studies. These studies involve a larger patient population to gather comprehensive safety and efficacy data.
Choice D rationale
Choosing appropriate patients to be involved in the study is primarily the responsibility of researchers and clinicians during the earlier phases of drug development, such as phase I and phase II studies.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A rationale
Heart failure occurs when the heart muscle cannot pump blood effectively, leading to a backup of blood and fluid buildup in the lungs, legs, and other parts of the body. This explanation is accurate and helps the patient understand the nature of their condition.
Choice B rationale
Reduced oncotic pressure due to increased protein levels is not a primary factor in heart failure. Heart failure is related to the heart’s inability to pump effectively, not protein levels affecting oncotic pressure.
Choice C rationale
Hydrostatic pressure pushing fluids out of the capillaries is not directly related to heart failure. In heart failure, the issue lies in the heart’s inability to pump blood efficiently, leading to fluid buildup rather than fluid being pushed out of capillaries.
Choice D rationale
The decrease in venous pressure from the backup of blood does not cause heart failure. Heart failure results from the heart’s inability to pump blood effectively, leading to increased pressure and fluid buildup, not a decrease in venous pressure.
Correct Answer is B
Explanation
Choice A rationale
Peripheral edema is more commonly associated with right-sided heart failure rather than left-sided. This is because right-sided heart failure leads to systemic venous congestion, causing fluid to accumulate in the peripheral tissues, particularly in the legs and ankles.
Choice B rationale
Pulmonary edema is a major concern in left-sided heart failure due to the inability of the left ventricle to effectively pump blood out to the systemic circulation. This results in blood backing up into the pulmonary veins, leading to fluid accumulation in the lungs.
Choice C rationale
Liver edema, or hepatomegaly, is more typically seen in right-sided heart failure, where the failure of the right ventricle causes blood to back up into the systemic circulation, affecting the liver and other organs.
Choice D rationale
Abdominal edema, or ascites, is also more associated with right-sided heart failure. This condition occurs due to increased pressure in the veins and capillaries, leading to fluid leakage into the abdominal cavity.
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