When involved in phase III drug evaluation studies, what responsibilities would the nurse have?
Working with animals who are given experimental drugs.
Conducting research to determine the effectiveness of the drug.
Monitoring and observing patients closely for adverse effects.
Choosing appropriate patients to be involved in the study.
The Correct Answer is C
Choice A rationale
Working with animals is typically done in preclinical trials before phase I studies in humans and is not part of phase III drug evaluation studies.
Choice B rationale
Conducting research to determine the effectiveness of the drug is part of phase II studies. Phase III studies focus more on confirming effectiveness, monitoring side effects, and comparing it to commonly used treatments.
Choice C rationale
Monitoring and observing patients closely for adverse effects is a key responsibility in phase III drug evaluation studies. These studies involve a larger patient population to gather comprehensive safety and efficacy data.
Choice D rationale
Choosing appropriate patients to be involved in the study is primarily the responsibility of researchers and clinicians during the earlier phases of drug development, such as phase I and phase II studies.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A rationale
Administering a non-steroidal anti-inflammatory drug (NSAID) is not a priority action for a patient who has received a narcotic analgesic. The priority should be to ensure the patient’s safety and prevent falls, which can occur due to the sedative effects of narcotics.
Choice B rationale
Putting side rails up and placing the bed in the lowest position is essential for patient safety. Narcotics can cause dizziness, drowsiness, and impaired coordination, increasing the risk of falls. Ensuring the bed is in the lowest position and side rails are up helps prevent injury if the patient tries to get up.
Choice C rationale
Encouraging fluids is beneficial for many patients, but it is not the priority action when a patient has received a narcotic analgesic. Hydration is important but secondary to ensuring the patient’s immediate safety.
Choice D rationale
Creating a restful, dark environment may help the patient rest, but it does not directly address the immediate safety needs of a patient who has received a narcotic analgesic. The focus should be on preventing falls and injury.
Correct Answer is D
Explanation
Choice A rationale
Taking medication at the first sign of nausea may be too late to prevent motion sickness as it takes time for the medication to be absorbed and take effect.
Choice B rationale
Taking medication just prior to takeoff might not give the drug enough time to be absorbed and start working effectively.
Choice C rationale
Taking medication just prior to boarding the flight may not provide sufficient time for the drug to reach its peak effectiveness.
Choice D rationale
Taking the medication at 0700 before leaving for the airport allows enough time for the drug to be absorbed and reach its peak effect, which is essential for preventing motion sickness during the flight.
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