The nursing instructor asks the student nurse to explain the action of sumatriptan.
What is the student's best response?

Choice A rationale

Serotonin does not compete with anticholinergic agents at muscarinic acetylcholine receptor sites; anticholinergics target these receptors to inhibit the parasympathetic nervous system.

Choice B rationale

Anticholinergics do not increase norepinephrine at the neuromuscular junction.

Choice C rationale

Nicotinic receptors are primarily affected by different classes of drugs, such as neuromuscular blockers.

Choice D rationale

Anticholinergics inhibit the actions of the parasympathetic nervous system by blocking muscarinic receptors, reducing bodily functions like saliva production, digestion, and urination.

Choice A rationale

This choice is correct. The side effects of paroxetine, including headaches, nervousness, and poor appetite, are common during the initial weeks of treatment and often decrease over time as the patient’s body adjusts to the medication. Reassuring the patient helps them continue the treatment without undue anxiety about these side effects, which are typically transient and manageable.

Choice B rationale

This choice is incorrect. Abruptly stopping paroxetine without consulting a healthcare provider is not recommended because it can lead to withdrawal symptoms and a possible relapse of depression or anxiety. The patient should only discontinue the medication under the guidance of a healthcare provider, who may suggest a gradual tapering off process to minimize withdrawal symptoms.

Choice C rationale

This choice is partially correct. Taking paroxetine with food can help mitigate some gastrointestinal side effects, such as nausea. However, it does not directly address headaches, nervousness, or poor appetite. Although taking the medication with food is a useful tip, it is not the most comprehensive advice for this particular situation.

Choice D rationale

This choice is incorrect. While adjusting the dose may be an option, it is premature to suggest this after only two weeks of treatment. The patient’s body may still be adjusting to the medication, and many side effects diminish with time. The decision to change the dosage should be made by the healthcare provider based on a thorough evaluation of the patient’s response to the treatment.