What nursing intervention is appropriate for a client with systemic lupus erythematosus (SLE)?

Choice A reason: This is not the correct answer because opioids are a class of medications that act on the opioid receptors in the brain and spinal cord to reduce pain perception and emotional response. Opioids do not have a direct effect on tissue inflammation or bone healing, but they can cause side effects such as constipation, nausea, sedation, respiratory depression, and addiction.

Choice B reason: This is not the correct answer because anticoagulants are a class of medications that prevent or reduce the formation of blood clots by interfering with the clotting factors or platelets. Anticoagulants do not have a direct effect on tissue inflammation or bone healing, but they can increase the risk of bleeding and hematoma formation, which can impair the blood supply and oxygen delivery to the injured tissues.

Choice C reason: This is the correct answer because NSAIDs are a class of medications that inhibit the enzyme cyclooxygenase (COX), which is involved in the synthesis of prostaglandins, which are inflammatory mediators that cause pain, swelling, and fever. NSAIDs can decrease tissue inflammation and pain, but they can also delay bone healing by reducing the formation of osteoblasts, which are cells that build new bone tissue.

Choice D reason: This is not the correct answer because narcotics are another term for opioids, which are a class of medications that act on the opioid receptors in the brain and spinal cord to reduce pain perception and emotional response. Narcotics do not have a direct effect on tissue inflammation or bone healing, but they can cause side effects such as constipation, nausea, sedation, respiratory depression, and addiction.

Choice A reason: Ischemia is a cause of a pressure ulcer, because it means reduced blood flow to the tissues, which can lead to tissue hypoxia, necrosis, and ulceration. Ischemia can result from factors such as compression, friction, shear, or vascular disease.

Choice B reason: Immobility is a cause of a pressure ulcer, because it means prolonged pressure on the bony prominences, which can impair blood flow and cause ischemia, tissue damage, and ulceration. Immobility can result from factors such as paralysis, injury, illness, or sedation.

Choice C reason: Poor nutrition is a cause of a pressure ulcer, because it means inadequate intake or absorption of nutrients, such as protein, calories, vitamins, and minerals, which are essential for tissue repair and wound healing. Poor nutrition can result from factors such as anorexia, malabsorption, or poverty.

Choice D reason: Moisture is a cause of a pressure ulcer, because it means excessive wetness or dampness of the skin, which can weaken the skin barrier, increase the risk of infection, and delay wound healing. Moisture can result from factors such as incontinence, perspiration, or wound drainage.

Choice E reason: Adequate perfusion is not a cause of a pressure ulcer, but rather a protective factor. Adequate perfusion means sufficient blood flow to the tissues, which can prevent ischemia, tissue damage, and ulceration. Adequate perfusion can be promoted by factors such as regular repositioning, pressure relief, and exercise.