Type 1 diabetes exhibits:
Genetic or environmental influence, but resistance to insulin.
Absolute deficit in insulin.
Genetic or environmental influence, but produce some insulin.
Resistance to insulin as well as no insulin production.
The Correct Answer is B
Choice A reason: Type 1 diabetes is characterized by an absolute deficiency of insulin due to autoimmune destruction of pancreatic beta cells. It is not primarily marked by insulin resistance, which is more characteristic of type 2 diabetes. The genetic and environmental factors in type 1 diabetes lead to a lack of insulin production, rather than resistance.
Choice B reason: In type 1 diabetes, there is an absolute deficit in insulin production. This is because the body's immune system attacks and destroys the insulin-producing beta cells in the pancreas. As a result, individuals with type 1 diabetes require exogenous insulin to manage their blood glucose levels.
Choice C reason: While type 1 diabetes has genetic and environmental influences, the condition results in an inability to produce insulin rather than partial insulin production. The autoimmune response in type 1 diabetes leads to the destruction of almost all beta cells, resulting in an absolute deficit of insulin.
Choice D reason: Type 1 diabetes does not typically exhibit both insulin resistance and no insulin production. While some individuals with type 1 diabetes may develop insulin resistance over time (a condition known as "double diabetes"), the hallmark feature of type 1 diabetes is the absolute deficiency of insulin due to the autoimmune destruction of beta cells.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A reason: Alpha cells of the pancreas do not produce insulin. Insulin is produced by the beta cells of the pancreas. Therefore, the absence of alpha cells would not affect insulin secretion.
Choice B reason: The primary function of alpha cells in the pancreas is to produce and secrete glucagon. Glucagon is a hormone that raises blood glucose levels by promoting the conversion of glycogen to glucose in the liver. Without alpha cells, the body would not be able to secrete glucagon, leading to issues with glucose regulation.
Choice C reason: Somatostatin and gastrin are not secreted by alpha cells. Somatostatin is produced by delta cells of the pancreas and other parts of the digestive system, while gastrin is primarily produced by G cells in the stomach lining. Therefore, the absence of alpha cells would not affect the secretion of somatostatin and gastrin.
Choice D reason: Pancreatic polypeptides are produced by PP cells (pancreatic polypeptide cells) in the pancreas. The absence of alpha cells would not impact the secretion of pancreatic polypeptides.
Correct Answer is C
Explanation
Choice A reason: Most patients with CNS tumors do not develop metastatic disease. Central nervous system (CNS) tumors, including brain tumors, typically do not metastasize outside the CNS. Instead, they grow and exert pressure on adjacent brain structures, leading to neurological symptoms.
Choice B reason: While brain tumors can be very deadly, the TNM classification system is not avoided due to the lethality of the tumors. The main reason for not using the TNM system is because the classification criteria do not align well with the unique aspects of brain tumors.
Choice C reason: Tumor size is less relevant than the location and histology for brain tumors. The location of the tumor within the brain and its histological characteristics (e.g., type, grade, and molecular features) are more critical for prognosis and treatment planning. Brain tumors can cause significant clinical issues even when small, depending on their location.
Choice D reason: Brain tumors can have a poor prognosis, but this is not the reason the TNM classification is not used. The classification system's limitation is primarily due to the fact that brain tumors' behavior and treatment considerations depend more on their location and histological features than on tumor size, nodal involvement, and metastasis, which are the focus of the TNM system.
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