The nurse is providing teaching for the family of a patient who has been newly diagnosed with Alzheimer disease (AD). Which statement by the family member indicates understanding of the teaching?

“Alzheimer disease affects memory but not personality.”

“With proper treatment, symptoms of this disease can be arrested.”

“The onset of Alzheimer disease is usually between 65 and 75 years.”

“Alzheimer disease is a chronic, progressive condition.”

Answer and Explanation

The Correct Answer is D

A) “Alzheimer disease affects memory but not personality.”
While memory loss is one of the hallmark symptoms of Alzheimer’s disease, the condition also significantly impacts other cognitive functions, including personality and behavior. As the disease progresses, patients often experience changes in mood, behavior, and personality, such as increased irritability, depression, or aggression.

B) “With proper treatment, symptoms of this disease can be arrested.”
Currently, there is no cure for Alzheimer’s disease, and while some treatments (like cholinesterase inhibitors) can help manage symptoms temporarily or slow their progression, the disease itself is not arrestable. The goal of treatment is to manage symptoms and improve quality of life, but it cannot stop the disease from advancing.

C) “The onset of Alzheimer disease is usually between 65 and 75 years.”
While Alzheimer’s disease typically affects older adults, this statement is too narrow. Alzheimer’s disease can begin earlier, sometimes in individuals in their 50s or 60s, particularly in cases of early-onset Alzheimer’s. The average age of onset for most people is around 65, but there is variability.

D) “Alzheimer disease is a chronic, progressive condition.”
Alzheimer’s disease is indeed chronic (lasting for years) and progressive (it worsens over time). It gradually destroys brain cells, leading to a decline in cognitive function, including memory, thinking, and reasoning skills. This is the fundamental nature of the disease

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Correct Answer is A

Explanation

A) Inhibit cyclooxygenase that is necessary for prostaglandin synthesis:
NSAIDs primarily work by inhibiting the enzyme cyclooxygenase (COX), which plays a crucial role in the conversion of arachidonic acid into prostaglandins. Prostaglandins are chemicals that promote inflammation, pain, and fever in response to injury or infection. By blocking COX, NSAIDs reduce the production of prostaglandins, thereby decreasing inflammation and alleviating pain and fever.

B) Exert direct actions to cause relaxation of smooth muscle:
NSAIDs do not directly cause the relaxation of smooth muscle. While some other classes of drugs (e.g., bronchodilators) target smooth muscle relaxation, NSAIDs primarily work by reducing the production of prostaglandins, which in turn alleviates inflammation and pain. They do not have a significant effect on smooth muscle tone itself.

C) Suppress prostaglandin activity by blocking tissue receptor sites:
NSAIDs do not block the receptor sites for prostaglandins; rather, they inhibit the cyclooxygenase enzyme, which is responsible for the synthesis of prostaglandins. This reduces the overall production of prostaglandins, rather than blocking their activity at the receptor level.

D) Interfere with neuronal pathways associated with prostaglandin action:
While NSAIDs reduce prostaglandin production, they do not directly interfere with neuronal pathways associated with prostaglandin action. They act primarily by inhibiting the cyclooxygenase enzyme to reduce the synthesis of prostaglandins at the site of injury or inflammation, rather than by modulating specific neural pathways.

A. Hypothalamus and the medulla B. Cranium and sacral area of the spinal cord C. Thoracic and lumbar section of the spinal cord D. Nerve membrane

Correct Answer is C

Explanation

A) Hypothalamus and the medulla: While the hypothalamus and medulla play critical roles in regulating autonomic functions and overall sympathetic nervous system activity, the primary origin of the sympathetic nervous system's neural impulses comes from the spinal cord, specifically in the thoracic and lumbar regions. The hypothalamus and medulla are involved in coordinating and regulating sympathetic activity rather than being the origin of the impulses themselves.

B) Cranium and sacral area of the spinal cord: The cranium and sacral regions are primarily associated with the parasympathetic nervous system, not the sympathetic nervous system. The parasympathetic nervous system's nerve fibers arise from the brainstem and the sacral region, while the sympathetic fibers originate from the thoracic and lumbar areas.

C) Thoracic and lumbar section of the spinal cord: The sympathetic nervous system originates in the thoracolumbar region of the spinal cord, which includes the thoracic and lumbar segments (T1-L2). These regions house the preganglionic neurons whose axons exit the spinal cord and synapse in sympathetic ganglia, leading to the sympathetic effects on organs and tissues. This makes the thoracic and lumbar sections the correct location for the origin of SNS impulses.

D) Nerve membrane: The nerve membrane, or the cellular membrane of individual neurons, is not the location where impulses originate. The origin of the impulses is in the central nervous system (CNS), specifically in the spinal cord for the sympathetic system, not at the level of the individual nerve membranes.

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The nurse is providing teaching for the family of a patient who has been newly diagnosed with Alzheimer disease (AD). Which statement by the family member indicates understanding of the teaching?

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Explanation

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Correct Answer is C

Explanation

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