The nurse is caring for a client diagnosed with chronic hepatitis who is receiving the medication lactulose. Which of these laboratory results would indicate the medication is achieving the desired therapeutic effect?
Increased serum albumin
Decreased serum bilirubin
Decreased serum ammonia
Decreased serum alanine aminotransferase (ALT)
The Correct Answer is C
Choice A Reason: Increased Serum Albumin
Increased serum albumin is not a direct indicator of the therapeutic effect of lactulose in patients with chronic hepatitis. Albumin is a protein made by the liver, and its levels can be affected by liver function. However, lactulose primarily works by reducing ammonia levels in the blood, not by increasing albumin levels. Normal serum albumin levels range from 3.5 to 5.5 grams per deciliter (g/dL). While improved liver function might eventually lead to increased albumin levels, this is not the primary therapeutic effect of lactulose.
Choice B Reason: Decreased Serum Bilirubin
Decreased serum bilirubin is also not a direct indicator of lactulose’s therapeutic effect. Bilirubin is a byproduct of the normal breakdown of red blood cells and is processed by the liver. Elevated bilirubin levels can indicate liver dysfunction, but lactulose’s main role is to reduce ammonia levels, not bilirubin. Normal serum bilirubin levels are typically between 0.1 to 1.2 milligrams per deciliter (mg/dL). While improved liver function might reduce bilirubin levels, this is not the primary goal of lactulose therapy.
Choice C Reason: Decreased Serum Ammonia
Decreased serum ammonia is the correct indicator of the therapeutic effect of lactulose in patients with chronic hepatitis. Lactulose is used to treat hepatic encephalopathy, a condition caused by high levels of ammonia in the blood due to liver dysfunction. Lactulose works by converting ammonia into ammonium, which is then excreted from the body. Normal serum ammonia levels are less than 50 micromoles per liter (µmol/L) in adults56. A decrease in serum ammonia levels indicates that lactulose is effectively reducing the toxic levels of ammonia in the blood, thereby achieving its desired therapeutic effect.
Choice D Reason: Decreased Serum Alanine Aminotransferase (ALT)
Decreased serum alanine aminotransferase (ALT) is not a direct indicator of lactulose’s therapeutic effect. ALT is an enzyme found in the liver that helps convert proteins into energy for liver cells. Elevated ALT levels can indicate liver damage. Normal ALT levels range from 7 to 56 units per liter (U/L). While improved liver function might reduce ALT levels, lactulose’s primary role is to reduce ammonia levels, not directly affect ALT.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Provide a quiet, low-stimulus environment
Choice A Reason:
Provide a quiet, low-stimulus environment
This is the correct answer. A quiet, low-stimulus environment helps to reduce the metabolic demands on the body and prevent overstimulation, which can trigger a thyroid crisis. Hyperthyroidism increases the body’s metabolic rate, and excessive stimulation can exacerbate symptoms and lead to a crisis. Therefore, creating a calm environment is crucial in managing hyperthyroidism and preventing complications.
Choice B Reason:
Keep the client NPO
Keeping the client NPO (nothing by mouth) is not typically necessary for preventing a thyroid crisis. While it may be required for certain procedures or if the client is experiencing severe symptoms, it is not a standard intervention for hyperthyroidism management. Therefore, this choice is not correct.
Choice C Reason:
Administer aspirin as prescribed for any sign of hyperthermia
Administering aspirin for hyperthermia is not recommended in clients with hyperthyroidism. Aspirin can increase free thyroid hormone levels by displacing thyroid hormones from their binding proteins, potentially worsening hyperthyroidism. Instead, other antipyretics like acetaminophen are preferred. Therefore, this choice is not correct.
Choice D Reason:
Observe the client carefully for signs of hypocalcemia
Observing for signs of hypocalcemia is not directly related to preventing a thyroid crisis. Hypocalcemia is more commonly associated with thyroidectomy or parathyroidectomy rather than hyperthyroidism itself. Therefore, this choice is not correct.
Correct Answer is ["B","C","E"]
Explanation
Choice A Reason:
Excessive salivation, also known as water brash, can occur in some cases of GERD, but it is not one of the most common symptoms. Water brash happens when the body produces extra saliva to neutralize the acid in the esophagus. While it can be associated with GERD, it is not as prevalent as other symptoms like heartburn or regurgitation.
Choice B Reason:
Dyspepsia, or indigestion, is a common symptom of GERD. It includes discomfort or pain in the upper abdomen, bloating, and nausea. Dyspepsia occurs because the stomach acid irritates the lining of the esophagus and stomach, leading to these uncomfortable sensations. Therefore, dyspepsia is a typical finding in patients with GERD.
Choice C Reason:
Regurgitation is a hallmark symptom of GERD. It involves the backflow of stomach contents into the esophagus and sometimes into the mouth, causing a sour or bitter taste. This symptom is due to the weakening or relaxation of the lower esophageal sphincter, which allows stomach acid to escape into the esophagus.
Choice D Reason:
Blood-tinged sputum is not a common symptom of GERD. While severe cases of GERD can lead to complications such as esophagitis or esophageal ulcers, which might cause bleeding, this is not typical in most GERD cases. Blood-tinged sputum would warrant further investigation to rule out other conditions such as infections or malignancies.
Choice E Reason:
Flatulence, or excessive gas, can be associated with GERD. The digestive process can be affected by the reflux of stomach acid, leading to increased gas production and bloating. While not as prominent as dyspepsia or regurgitation, flatulence can still be a symptom experienced by patients with GERD.
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