The nurse has administered warfarin 2.5 mg orally daily for three days to a client who has deep vein thrombosis. The client's International Normalized Ratio (INR) today is 5.0. The nurse notifies the healthcare provider because today's dose of the medication should be:
Switched to heparin.
Given as prescribed.
Increased.
Held.
The Correct Answer is A
Choice A Reason:
Switching to heparin is not the standard response for a high INR. Heparin may be used in conjunction with warfarin when starting anticoagulation therapy, but it is not typically used as a substitute in response to an elevated INR.
Choice B Reason:
Giving the dose as prescribed would not be appropriate when the INR is significantly above the therapeutic range. Continuing the same dose could increase the risk of bleeding complications.
Choice C Reason:
Increasing the dose would be contraindicated as the INR is already too high. Increasing the warfarin dose would further elevate the INR and increase the risk of bleeding.
Choice D Reason:
Holding the dose is the correct action when the INR is significantly above the therapeutic range, which is generally between 2.0 to 3.0 for most indications. The healthcare provider should be notified, and the warfarin dose should be held until the INR returns to the therapeutic range. Vitamin K may also be administered to help lower the INR more quickly if necessary.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A Reason
While hypertension can contribute to the development of PAD, it does not directly cause fats to deposit in the arteries. Hypertension can damage the arterial walls, making them more susceptible to atherosclerosis, but it is not the primary mechanism of PAD development.
Choice B Reason
Excess fats in the diet can contribute to atherosclerosis, which is the accumulation of plaques in the arterial walls. However, the fats do not simply get stored; they combine with other substances, including calcium and inflammatory cells, to form plaques that can restrict blood flow.
Choice C Reason
This statement is the most accurate. PAD is primarily caused by atherosclerosis, which is the buildup of plaques formed by fats, cholesterol, calcium, and other substances in the blood. These plaques can harden and narrow the arteries, leading to reduced blood flow to the extremities. The process can be exacerbated by factors such as smoking, diabetes, and high cholesterol.
Arterial spasms can occur, but they are not the typical cause of chronic PAD. Spasms are more often associated with conditions like Raynaud's phenomenon or can be a response to stress or cold temperatures. PAD is usually a result of progressive atherosclerosis rather than intermittent spasms.

Correct Answer is D
Explanation
Choice A reason:
While polyhydramnios can be associated with congenital anomalies or fetal distress, it is not a direct indication of these conditions. Polyhydramnios refers specifically to the excessive accumulation of amniotic fluid. Congenital anomalies may lead to polyhydramnios if they affect the fetus's ability to swallow and process amniotic fluid normally, but the presence of polyhydramnios alone does not confirm these conditions.
Choice B reason:
Elevated levels of alpha-fetoprotein (AFP) in the amniotic fluid can be indicative of neural tube defects or other fetal abnormalities, but they are not a defining characteristic of polyhydramnios. Normal AFP levels in amniotic fluid at 15 to 21 weeks' gestation range from 10 to 150 ng/ml. Polyhydramnios is diagnosed based on the volume of amniotic fluid, not the AFP levels.
Choice C reason:
Carrying more than one fetus can lead to an increased amount of amniotic fluid, potentially resulting in polyhydramnios. However, the diagnosis of polyhydramnios itself does not imply a multiple gestation pregnancy. It simply indicates that there is more amniotic fluid than usual.
Choice D reason:
Polyhydramnios is defined as an excessive amount of amniotic fluid. It is typically diagnosed when the amniotic fluid index (AFI) exceeds 24 cm or the single deepest pocket (SDP) measures more than 8 cm. This condition can occur due to various reasons, including fetal anomalies, maternal diabetes, and other medical conditions.

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