The nurse evaluates a client's response to hemodialysis.
Which finding indicates an expected outcome?

Administering phenytoin requires applying knowledge of intravenous drug compatibility and cardiovascular safety profiles. The nurse must prioritize monitoring for life-threatening complications associated with rapid infusion, specifically focusing on the drug's narrow therapeutic index and its significant irritant properties.

Choice A rationale

Phenytoin is highly unstable and will precipitate if mixed with dextrose solutions. It must only be diluted with 0.9 percent sodium chloride. Incorrect dilution can lead to crystalline emboli and loss of drug efficacy during administration.

Choice B rationale

Intravenous phenytoin is a known vesicant that can cause purple glove syndrome if administered into small peripheral veins like those in the hand. Use of a large-bore catheter in a large vein or central line is preferred.

Choice C rationale

Rapid infusion of phenytoin can lead to severe cardiovascular collapse, including hypotension and fatal dysrhythmias. The infusion rate should not exceed 50 mg per minute to allow the heart to tolerate the drug's membrane-stabilizing effects safely.

Choice D rationale

The standard therapeutic range for phenytoin is 10 to 20 mcg per mL, not 20 to 30 mg per mL. Levels exceeding 20 mcg per mL often result in toxicity, characterized by nystagmus, ataxia, and decreased mental status.

Identifying appropriate placement for infectious clients requires understanding transmission-based precautions. Tuberculosis is an airborne pathogen requiring specialized ventilation to prevent the spread of droplet nuclei. Knowledge of negative pressure systems and environmental safety standards is essential for preventing nosocomial transmission to others.

Choice A rationale

Placing a client with active tuberculosis in a semi-private room violates airborne precautions. This increases the risk of horizontal transmission to immunocompromised roommates via microscopic droplet nuclei that remain suspended in the air for several hours.

Choice B rationale

Airborne infection isolation rooms require a minimum of 6 to 12 air exchanges per hour. Exhausting air directly outdoors or through HEPA filters prevents contaminated air from recirculating into common hallways or other patient care areas.

Choice C rationale

Admission to an intensive care unit is reserved for hemodynamically unstable clients or those requiring advanced mechanical ventilation. Tuberculosis alone is not an indication for critical care unless the client exhibits acute respiratory failure or septic shock.

Choice D rationale

While proximity to the nurses' station allows for frequent observation, it does not address the physiological requirement for negative pressure ventilation. Standard medical-surgical rooms lack the engineering controls necessary to contain airborne bacilli within the specific room.