(Select all that apply) A client is receiving ciprofloxacin IV for a severe infection caused by Pseudomonas aeruginosa.
Which of the following laboratory tests should the nurse monitor for adverse effects of this medication?

This is because penicillin G is a beta-lactam antibiotic that can cause severe allergic reactions in some people, such as anaphylaxis, rash, or angioedema. Therefore, the nurse should always check for any history of allergies before administering penicillin G or any other beta-lactam antibiotic.

Choice A is wrong because checking the client’s temperature is not a priority action before giving penicillin G.Although fever is a common sign of meningitis, it does not affect the administration of penicillin

Choice B is wrong because assessing the client’s level of consciousness is not a priority action before giving penicillin G.Although altered mental status is a common sign of meningitis, it does not affect the administration of penicillin

Choice D is wrong because obtaining a blood sample for culture and sensitivity is not a priority action before giving penicillin G.Although culture and sensitivity tests are important to identify the causative organism and the appropriate antibiotic, they should not delay the initiation of empiric therapy for meningitis.Penicillin G is effective against Streptococcus pneumoniae, which is the most common cause of bacterial meningitis in adults.

Ciprofloxacin is an antibiotic that can cause various side effects, some of which are serious and may be permanent.

The nurse should monitor the following laboratory tests for adverse effects of this medication:

• Liver function tests: Ciprofloxacin can cause hepatotoxicity, which is damage to the liver cells.Liver function tests can detect abnormal levels of enzymes or bilirubin that indicate liver injury.

• Serum creatinine levels: Ciprofloxacin can cause nephrotoxicity, which is damage to the kidney cells.

Serum creatinine levels can measure how well the kidneys are filtering waste products from the blood.Elevated serum creatinine levels indicate impaired kidney function.

• Complete blood count: Ciprofloxacin can cause hematologic disorders, such as anemia, leukopenia, thrombocytopenia, or pancytopenia.

A complete blood count can evaluate the number and quality of red blood cells, white blood cells, and platelets in the blood.Abnormal blood counts can increase the risk of bleeding, infection, or fatigue.

Choice B is wrong because ciprofloxacin does not affect blood glucose levels directly.

However, ciprofloxacin can interact with some oral antidiabetic drugs and increase the risk of hypoglycemia or hyperglycemia.Therefore, the nurse should monitor the blood glucose levels of diabetic patients who are taking ciprofloxacin and other antidiabetic drugs.

Choice E is wrong because ciprofloxacin does not affect thyroid function tests directly.

However, ciprofloxacin can interact with some thyroid hormone replacement drugs and decrease their absorption or efficacy.Therefore, the nurse should monitor the thyroid function tests of patients who are taking ciprofloxacin and thyroid hormone replacement drugs.