Phenytoin has a narrow therapeutic index. The nurse recognizes that this characteristic indicates which of these?

The phenytoin has a low chance of being effective.

There is no difference between safe and toxic plasma levels.

Avery small dosage can result in the desired therapeutic effect.

The safe and the toxic plasma levels of the drug are very close to each other.

Answer and Explanation

The Correct Answer is D

D. Therapeutic index refers to the doses that results in desired outcome with adverse effects. It is between the safe and toxic levels. Narrow therapeutic level means the two are very close.
A. How effective a drug is termed as efficacy
B. Such a drug does not exist as it is not safe
C. Effectiveness of very small dose is termed as potency

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Free Nursing Study Resources

Correct Answer is ["56"]

Explanation

Flow rate (gtt/min) = Volume (mL)/Time (min) ×Drop factor (gtts/mL)

A. Avoid people who have infections. B. Practice frequent hand hygiene. C. Do not drink alcoholic beverages while taking this medication. D. Smoking will not affect this medication. E. Expect to feel the medication's effects immediately.

Correct Answer is ["A","B","C"]

Explanation

Methotrexate inhibits the synthesis of purines. Purines and pyrimidines are the building blocks of DNA synthesis in every cell in the body. It affects the production of white blood cells and hence lowers the immunity and hence the client is at a higher risk for infections

Avoiding infected persons and hand hygiene prevents infections. Alcohol should be avoided as it increases the risk of liver damage

E-it takes several weeks to months to produce its effects

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Phenytoin has a narrow therapeutic index. The nurse recognizes that this characteristic indicates which of these?

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Naxlex Comprehensive Predictor Exams

A client with oliguria has an order for 1000 mL of 0.9% NS over 3 hours. The tubing drop factor is 10 gtt/mL. How many gtt/min should be given? (Round to the nearest whole number. use a leading zero if it applies. Do not use a trailing zero.)

Correct Answer is ["56"]

Explanation

A nurse is providing teaching a client who has rheumatoid arthritis and a new prescription for methotrexate. Which of the following instructions should the nurse include? (Select all that apply.)

Correct Answer is ["A","B","C"]

Explanation

When taking a telephone order for a medication, which action by the nurse is most appropriate?

A nurse is assessing a client IS min after administering morphine sulfate 2 mg via IV push. The nurse should identify which of the following findings as an adverse effect of the medication?

A client has been taking iron supplements for anemia for 2 months. During a follow-up assessment, the nurse will observe for which therapeutic response?

A client tells the nurse that he is having nausea and decreased appetite during drug therapy with a tetracycline antibiotic. Which statement is the nurse's best advice to the client?

Before administering any medication, what is the nurse's priority action regarding client safety?

A client is receiving high doses of methotrexate and is experiencing severe bone marrow suppression. The nurse expects which intervention to be ordered with this drug to reduce this problem?

A nurse is providing teaching to a client who has seizures and a new prescription for phenytoin. Which of the following information should the nurse provide?

A client is suffering from tendonitis of the knee. The nurse is reviewing the client's medication administration record and recognizes that which adjuvant medication is most appropriate for this type of pain?