A client is receiving high doses of methotrexate and is experiencing severe bone marrow suppression. The nurse expects which intervention to be ordered with this drug to reduce this problem?
Therapy with filgrastim
Leucovorin rescue
A transfusion of whole blood
Administration of allopurinol
The Correct Answer is B
B. methotrexate is a dihydrofolate reductase inhibitor which inhibits synthesis of building block for DNA synthesis and repair
A. Filgrastim is a growth factor used to boost neutrophil production
C. Transfusion-maybe necessary in the case of severe anemia
D. Allopurinol is an anti-uricemic agent used in gout
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
B. Rationale- Beta 2 adrenergic receptors are found on the airways. Beta adrenergic agonists bind on them to stimulate bronchial dilatation relieving obstruction in airway obstructive diseases.
A. Alpha 1 adrenergic receptors are found on the blood vessels
C. Beta receptors are found on the myocardium
D. Dopaminergic receptors are found in the brain
Correct Answer is ["167"]
Explanation
Dose=Weight in kg× Dose in mg/kg
Weight in kg= 111.13kg
Dose= 1.5 * 111.13
= 166.695
= 167mg
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