A client is receiving high doses of methotrexate and is experiencing severe bone marrow suppression. The nurse expects which intervention to be ordered with this drug to reduce this problem?
Therapy with filgrastim
Leucovorin rescue
A transfusion of whole blood
Administration of allopurinol
The Correct Answer is B
B. methotrexate is a dihydrofolate reductase inhibitor which inhibits synthesis of building block for DNA synthesis and repair
A. Filgrastim is a growth factor used to boost neutrophil production
C. Transfusion-maybe necessary in the case of severe anemia
D. Allopurinol is an anti-uricemic agent used in gout
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Disulfiram blocks the metabolism of alcohol leading to unpleasant effects such as flushing, apprehension, headache, nausea and vomiting
A. Alcohol containing substances will cause the unpleasant effect when consumed
B. Disulfiram prevent metabolism of alcohol and hence has no similar effects to alcohol
C. When taken with warfarin, it increases the risk of bleeding
Correct Answer is A
Explanation
A. morphine can cause respiratory depression
B. Not relevant to morphine administration
C. Important assessment but not priority
D. not directly related to morphine administration
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