A client is receiving high doses of methotrexate and is experiencing severe bone marrow suppression. The nurse expects which intervention to be ordered with this drug to reduce this problem?
Therapy with filgrastim
Leucovorin rescue
A transfusion of whole blood
Administration of allopurinol
The Correct Answer is B
B. methotrexate is a dihydrofolate reductase inhibitor which inhibits synthesis of building block for DNA synthesis and repair
A. Filgrastim is a growth factor used to boost neutrophil production
C. Transfusion-maybe necessary in the case of severe anemia
D. Allopurinol is an anti-uricemic agent used in gout
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
D. smoking increases acid production counteracting the effects of cimetidine
A. Cimetidine should be taken with meals
B. Other medications including antacids can be taken 2hrs after cimetidine
C. Water has no effect on effectiveness of cimetidine
Correct Answer is C
Explanation
Lithium reduces the concentration of urine leading to sodium and water loss
Other options not directly related to lithium use
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