Patient Data
For each medication used to treat gout, choose the most likely therapeutic outcome and the teaching associated with the medication.
Colchicine
Naproxen
Prednisone
Allopurinol
The Correct Answer is {"A":{"answers":"A, E"},"B":{"answers":"C, E"},"C":{"answers":"C, E"},"D":{"answers":"D, G"}}
Colchicine is used in severe acute gout attack to minimize pain at the joint. Colchicine's mechanism of action involves interfering with the inflammatory process by binding to tubulin, a protein essential for the formation of microtubules within cells.
Prednisone is a corticosteroid with anti-inflammatory properties. It reduces inflammation caused by urate crystals.
Naproxen is a nonsteroidal anti-inflammatory drug (NSAID). It interferes with the inflammatory process in gout reducing pain. The use of naproxen and prednisone with alcohol reduces their effectiveness leading to suboptimal pain relief.
Allopurinol is a lipid lowering agent. It prevents the formation of uric acid lowering the deposition of urate crystals at the joint(s). Missing a dose of allopurinol leads to subtherapeutic blood levels and increased risk of acute gout attacks.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
D Methotrexate is a disease-modifying antirheumatic drug (DMARD) commonly used in the treatment of RA to slow down the progression of joint damage and reduce inflammation. Aspirin, on the other hand, is often used to manage symptoms such as pain and inflammation. Combining these two medications addresses both the underlying disease process and symptom control, respectively, in the management of RA
A While both methotrexate and aspirin have potential side effects, they affect different aspects of rheumatoid arthritis treatment. Methotrexate is primarily used to slow disease progression, while aspirin is used for symptom management.
B Methotrexate and aspirin do not directly interact to reduce each other's side effects.
C While both methotrexate and aspirin have their own roles in the treatment of rheumatoid arthritis, there is no evidence to suggest that methotrexate enhances the effectiveness of aspirin. They work through different mechanisms and target different aspects of RA management.
Correct Answer is C
Explanation
C. Cushing's syndrome often leads to central (truncal) obesity, characterized by fat accumulation around the abdomen and face, while the extremities may appear relatively thin due to muscle wasting. This distribution of fat and muscle wasting contributes to the characteristic "moon face" appearance seen in individuals with Cushing's syndrome.
A. Visible swelling of the neck with no pain is not typically associated with Cushing's syndrome. Swelling of the neck may be indicative of other conditions such as goiter or thyroid nodules.
B. Warm, soft, moist, salmon-colored skin is not typically associated with Cushing's syndrome. Instead, individuals with Cushing's syndrome may exhibit thin, fragile, and easily bruised skin due to the effects of cortisol on collagen synthesis and skin integrity.
D. Husky voice and hoarseness are not typically associated with Cushing's syndrome. These symptoms may be indicative of vocal cord dysfunction or other conditions affecting the larynx or vocal cords.
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