Naloxone is effective because of which action?

Increasing the excretion of morphine sulfate by altering serum pH.

Preventing activation of opioid receptors through antagonist actions.

Regulating the sensitivity of opioid receptors by neurochemical alterations.

Countering the effects of morphine sulfate by agonist actions.

Answer and Explanation

The Correct Answer is B

a) Naloxone does not increase the excretion of opioids by altering serum pH; its primary action is at the receptor level.

b) Naloxone is an opioid receptor antagonist, meaning it blocks or prevents the activation of opioid receptors. This is how it counteracts the effects of opioids like morphine.

c) Naloxone does not regulate the sensitivity of opioid receptors by neurochemical alterations. Its action is more direct as an antagonist.

d) Naloxone is not an agonist; it does not produce opioid-like effects. Instead, it competes with opioids for receptor binding and blocks their effects.

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Correct Answer is ["A","C","D","E"]

Explanation

a) Liver disease can affect drug metabolism and clearance, influencing the response to medications.

b) Gender may play a role in drug response, as there are some gender-related differences in drug metabolism and distribution.

c) Height can influence drug dosing, especially for medications with weight-based dosing.

d) Age is a crucial factor in drug response, as the metabolism and elimination of drugs can vary across different age groups.

e) Genetic factors, including variations in drug-metabolizing enzymes and drug receptors, can significantly impact an individual's response to a drug.

A. "My warfarin dose may need to be readjusted when I take a course of antibiotics." B. "I should expect pink urine due to metabolic bi-products of the dye used in this medication." C. "I should eat spinach to increase my iron count if my INR goes below two." D. "Herbal remedies are fine, but I shouldn't take aspirin without consulting my provider."

Correct Answer is A

Explanation

A) Antibiotics can interact with warfarin, potentially affecting the INR, so dose adjustments may be necessary.

B) Pink urine is not an expected side effect of warfarin; this statement is inaccurate.

C) Eating spinach to increase iron count is not a relevant action related to warfarin or INR levels.

D) Warfarin interacts with many substances, including herbal remedies and aspirin. Notifying the provider before taking new medications or supplements is crucial for proper management.

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Naloxone is effective because of which action?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

Which variables can help determine the client's response to a drug? (Select all that apply.)

Correct Answer is ["A","C","D","E"]

Explanation

Which statement by a client indicates an understanding of self-care precautions when taking warfarin?

Correct Answer is A

Explanation

A client who reports routine consumption of more than three alcoholic beverages per day asks about taking acetaminophen when needed for occasional recurrent pain. What will the nurse tell the client?

Which of these findings would cause the nurse to hold the administration of oral metoprolol 25 mg?

A client who is suffering from an acute gout attack wants to know how colchicine differs from probenecid and allopurinol in its actions. Which of these statements shows the need for further teaching regarding the purpose and use of these medications?

A nurse is preparing discharge teaching for a client who will be going home on warfarin. Which of these client statements indicates the need for further instruction?

A client weighs 214 lb. What is the clients weight in kg? (Record answer to the nearest tenth, or one decimal place. Do not use a trailing zero.)

A pregnant client asks the nurse if she can take antihistamines for seasonal allergies during her pregnancy. What will the nurse tell the client?

Parents ask the nurse why an over-the-counter cough suppressant with sedative side effects is not recommended for infants. Which response by the nurse is correct?

What should the nurse advise a client on spironolactone regarding necessary self-care?