A client who is suffering from an acute gout attack wants to know how colchicine differs from probenecid and allopurinol in its actions. Which of these statements shows the need for further teaching regarding the purpose and use of these medications?
Allopurinol prevents the synthesis of uric acid.
All of these medications should be taken concurrently during an acute attack, and non-steroidal anti-inflammatory drugs (NSAIDs) should be added for pain control.
Colchicine reduces inflammation caused by uric acid.
Probenecid facilitates the elimination of uric acid in the nephrons.
The Correct Answer is B
A) Allopurinol inhibits the synthesis of uric acid, preventing its formation.
B) Colchicine is typically used for gout flares and reduces inflammation but is not usually taken concurrently with probenecid and allopurinol. NSAIDs or corticosteroids are often used for pain control during acute attacks.
C) Colchicine is known for its anti-inflammatory properties but does not prevent uric acid synthesis or facilitate its elimination.
D) Probenecid increases the excretion of uric acid in the urine.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
a) Requesting central venous access is not the first-line response to signs of redness, pain, and irritation at the current infusion site. It's essential to address the immediate issue first.
b) Continuing the infusion while elevating the arm may exacerbate the symptoms and is not an appropriate action when there are signs of localized irritation.
c) Stopping the infusion and selecting an alternate intravenous site is the correct action to prevent further complications and assess the cause of the irritation.
d) Applying warm packs and infusing the medication at a slower rate may not be sufficient to address the observed redness and pain, and an alternate site should be considered.
Correct Answer is ["A","B"]
Explanation
A) Hold metformin 24 hours to 48 hours before the CT. This is correct because it reduces the chance of metformin accumulating in the blood and causing lactic acidosis when combined with the contrast dye.
B) Hold metformin 48 hours after the CT. This is also correct because it allows time for the contrast dye to be eliminated from the body before resuming metformin.
C) Double the metformin dose after the CT. This is incorrect and dangerous because it can cause hypoglycemia, low blood sugar, which can lead to confusion, seizures, coma, or death. D) Take metformin as scheduled the day of the CT. This is incorrect and risky because it can result in high levels of metformin in the blood when mixed with the contrast dye, increasing the likelihood of lactic acidosis.
E) Resume metformin at half dose after the CT. This is incorrect and unnecessary because there is no evidence that reducing the dose of metformin after a CT scan with contrast dye has any benefit or reduces any harm.
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