Melanocytes give rise to the pigment melanin, which is responsible for skin color. Where can the melanocytes be found?

A. Smoking causes you to cough frequently, and the wound might get infected by sputum.

While smoking can indeed contribute to respiratory issues like coughing, linking this directly to wound infection by sputum is not the most accurate explanation of how smoking affects wound healing. The primary concern with smoking and wound healing lies in its effects on circulation and tissue oxygenation rather than the risk of infection due to coughing.

B. Nicotine causes vasoconstriction, so your wound might not get enough blood flow to heal.

This is the best response among the options provided. Nicotine, a major component of cigarette smoke, is known to constrict blood vessels (vasoconstriction). This constriction reduces blood flow to the wound site, leading to decreased delivery of oxygen and nutrients necessary for proper wound healing. It addresses the direct physiological impact of smoking on wound healing and provides a clear explanation for the client.

C. Nicotine causes tar to build up in the wound, and it will impair healing.

While nicotine and other components of tobacco smoke can have detrimental effects on healing, particularly through vasoconstriction, the explanation about tar building up in the wound is not entirely accurate. Tar is more associated with lung damage from smoking rather than direct buildup in external wounds. Therefore, this response is less specific and may confuse the client about the actual mechanism of how smoking affects wound healing.

D. Smoking is bad, and you should stop right away.

While this response emphasizes the importance of smoking cessation, it lacks specificity in explaining how smoking impacts wound healing. Providing specific information about vasoconstriction due to nicotine, as mentioned in option B, would be more helpful in helping the client understand the direct effects of smoking on their chronic wound and why cessation is crucial.

A. Cardiac arrest related to septic shock:

Septic shock can occur in burn patients due to the breakdown of the skin barrier, which allows pathogens to enter the bloodstream and cause systemic infection. However, while septic shock is a serious complication of burn injuries, it is not the primary cause of death in the emergent phase. Septic shock can lead to multiple organ failure and contribute to mortality, but it is often a later complication rather than an immediate cause in the emergent phase.

B. Infection:

Infections are a significant concern in burn patients, especially as the burn wound provides an ideal environment for bacterial growth. However, infections typically contribute more significantly to mortality in the later phases of burn care rather than in the emergent phase. In the emergent phase, hypovolemic shock and other immediate complications have a greater impact on mortality.

C. Adrenal failure:

Adrenal failure, specifically acute adrenal insufficiency or Addisonian crisis, can occur in burn patients due to the stress response and corticosteroid depletion. While adrenal insufficiency is a concern in severe burn cases, it is not the primary cause of death in the emergent phase requiring referral to a burn center.

D. Hypovolemic shock and renal failure:

Hypovolemic shock is a critical concern in the emergent phase of burn trauma because burns can lead to significant fluid loss and electrolyte imbalances. Hypovolemic shock results from insufficient circulating blood volume, leading to inadequate perfusion of organs and tissues, which can be life-threatening. Additionally, renal failure can develop due to hypovolemia, decreased cardiac output, and the release of inflammatory mediators, leading to acute kidney injury (AKI). Hypovolemic shock and subsequent renal failure are major contributors to mortality in the emergent phase of burn trauma, necessitating prompt referral to a burn center for specialized care.