Males are more likely than females to be affected by:
Autosomal-recessive disorders
Autosomal-dominant disorders
Chromosomal nondisjunction
X-linked (Sex) disorders
The Correct Answer is D
Choice A reason: Autosomal-recessive disorders affect both males and females equally because the gene in question is located on one of the autosomes (non-sex chromosomes). Each individual has two copies of each autosomal gene, one from each parent. An autosomal-recessive disorder manifests when an individual inherits two copies of a mutant gene, one from each parent. Therefore, gender does not influence the likelihood of being affected.
Choice B reason: Autosomal-dominant disorders also affect both males and females equally. These disorders occur when a single copy of a mutant gene on an autosome is sufficient to cause the disorder. Since autosomes are present in both males and females equally, the likelihood of inheriting an autosomal-dominant disorder is not influenced by gender.
Choice C reason: Chromosomal nondisjunction refers to errors in cell division that result in an abnormal number of chromosomes. While some conditions resulting from chromosomal nondisjunction can show gender bias (such as Turner syndrome affecting females and Klinefelter syndrome affecting males), it is not accurate to say that males are generally more likely than females to be affected by chromosomal nondisjunction.
Choice D reason: X-linked (sex-linked) disorders are more likely to affect males than females because the gene causing the disorder is located on the X chromosome. Males have one X and one Y chromosome (XY), while females have two X chromosomes (XX). If a male inherits a mutant gene on the X chromosome, he will express the disorder because he does not have a second X chromosome to mask the effect. In contrast, females would need two copies of the mutant gene (one on each X chromosome) to express the disorder, making it less likely for them to be affected.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A reason: Abnormally dilated arteries and veins, also known as aneurysms and varicose veins respectively, can occur due to various conditions. However, they are not the primary cause of stable angina and atherosclerosis. Aneurysms involve an abnormal widening or ballooning of a portion of an artery due to weakness in the wall of the blood vessel, while varicose veins refer to enlarged, twisted veins commonly found in the legs. These conditions do not directly cause the chronic narrowing of arteries that characterize atherosclerosis and lead to stable angina.
Choice B reason: Deep vein thrombosis (DVT) is a condition where a blood clot forms in a deep vein, usually in the legs. Although DVT is a serious medical condition that can lead to complications such as pulmonary embolism if the clot travels to the lungs, it is not related to the pathophysiology of atherosclerosis or stable angina. DVT involves venous circulation, whereas atherosclerosis and angina involve the arterial system, specifically the coronary arteries.
Choice C reason: Abnormal thickening and hardening of blood vessel walls, also known as atherosclerosis, is the primary cause of stable angina. Atherosclerosis is characterized by the buildup of plaque within the arterial walls, leading to their hardening and narrowing. This process reduces blood flow to the heart muscle, causing ischemia, which presents as chest pain, known as angina. Stable angina is a symptom of this chronic condition, which can lead to more severe cardiovascular events if left untreated.
Choice D reason: Autonomic nervous system dysfunction involves abnormalities in the autonomic nervous system, which controls involuntary bodily functions such as heart rate, blood pressure, and digestion. While autonomic dysfunction can contribute to various cardiovascular issues and symptoms such as irregular heartbeats or blood pressure changes, it is not the underlying cause of atherosclerosis or stable angina. Atherosclerosis is primarily a disease of the arterial walls, while autonomic dysfunction pertains to the regulation of bodily systems.
Correct Answer is C
Explanation
Choice A reason: Protein restriction is not a primary treatment for prerenal kidney injury. While managing protein intake can be important in chronic kidney disease to reduce the workload on the kidneys, it is not directly relevant to the acute management of prerenal kidney injury, which primarily involves restoring adequate blood flow to the kidneys.
Choice B reason: Potassium supplementation is not typically necessary for prerenal kidney injury. In fact, in many cases of kidney injury, there is a risk of hyperkalemia (elevated potassium levels) due to reduced kidney function. Therefore, potassium levels need to be monitored, but supplementation is not a standard treatment.
Choice C reason: Fluid administration to increase cardiac output is the appropriate therapy for prerenal kidney injury. Prerenal kidney injury is caused by reduced blood flow to the kidneys, often due to factors like hypovolemia (low blood volume) or heart failure. Administering fluids helps to restore adequate blood flow and perfusion to the kidneys, which can improve kidney function and resolve the prerenal injury.
Choice D reason: Fluid restriction is not appropriate for prerenal kidney injury, which is characterized by reduced blood flow to the kidneys. In cases where hypovolemia or low cardiac output is the cause, restricting fluids would worsen the condition. Instead, increasing fluid intake helps to restore adequate perfusion to the kidneys.
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