Calculate the flow rate in gtt/min using the formula method. Administer 2.500 mL. D5 0.33% NS in 8 hr. The drop factor is 15 grt/mL

A) Simvastatin:
Simvastatin is a medication used to lower cholesterol levels by inhibiting HMG-CoA reductase, an enzyme involved in the production of cholesterol in the liver. It is not an angiotensin-converting enzyme (ACE) inhibitor. Therefore, it does not have a direct effect on blood pressure or the renin-angiotensin system.

B) Losartan:
Losartan is an angiotensin II receptor blocker (ARB), not an ACE inhibitor. Like ACE inhibitors, ARBs are used to treat conditions like hypertension and heart failure, but they work differently by blocking the receptors that angiotensin II binds to, rather than inhibiting the enzyme that converts angiotensin I to angiotensin II.

C) Quinapril:
Quinapril is an ACE inhibitor. ACE inhibitors block the enzyme angiotensin-converting enzyme, which converts angiotensin I into angiotensin II, a potent vasoconstrictor. By inhibiting this conversion, ACE inhibitors like quinapril help lower blood pressure, reduce strain on the heart, and treat conditions like hypertension and heart failure.

D) Metoprolol:
Metoprolol is a beta-blocker, not an ACE inhibitor. It works by blocking beta-adrenergic receptors in the heart, which helps to lower heart rate and blood pressure. It is often used in the management of hypertension, heart failure, and to prevent heart attacks, but it does not affect the renin-angiotensin system like ACE inhibitors.

A) Flushing of the face:
Flushing is a common and usually harmless side effect of nitroglycerin, caused by its vasodilation properties. It often resolves quickly and is not typically a cause for concern. While it can be uncomfortable, it is not a sign of a serious problem that would require immediate medical attention.

B) Dizziness upon standing:
Dizziness upon standing (orthostatic hypotension) is a known side effect of nitroglycerin due to its blood pressure-lowering effects. It typically occurs when the patient rises too quickly from a sitting or lying position. While it can be uncomfortable and may cause the patient to feel lightheaded, it is usually not an emergency and can often be managed by rising slowly. If dizziness persists or is severe, the healthcare provider should be notified, but it is not an immediate emergency.

C) Persistent chest pain that lasts longer than 15 minutes:
Chest pain lasting longer than 15 minutes could indicate a myocardial infarction (heart attack) rather than stable angina, even if nitroglycerin has been administered. Chest pain that is not relieved by nitroglycerin or persists for more than a few minutes is an emergency situation and should be reported immediately to the healthcare provider or emergency services.

D) Mild headache:
Headache is a common and benign side effect of nitroglycerin, caused by its vasodilation effect. It is usually mild and transient and does not require immediate medical attention. In most cases, the headache improves over time or with the use of over-the-counter pain relievers, and it is not a reason to contact the healthcare provider unless it becomes severe or persistent.