An adult client with extreme fatigue, weight gain, cold intolerance, and bradycardia is diagnosed with hypothyroidism. Which laboratory findings is this client likely to exhibit?

A. Severely decreased GFR:

In stage 4 chronic kidney disease (CKD), the glomerular filtration rate (GFR) is indeed severely decreased. Stage 4 CKD is characterized by a GFR between 15 and 29 mL/min/1.73 m² according to the Kidney Disease Outcomes Quality Initiative (KDOQI) guidelines. At this stage, there is significant kidney damage, resulting in a substantial reduction in kidney function and GFR. Clients with stage 4 CKD require close monitoring and management to prevent further progression of kidney disease and associated complications.

B. Mildly decreased GFR:

This choice is incorrect. Stage 4 CKD is not associated with a mildly decreased GFR. A mildly decreased GFR would typically be indicative of earlier stages of CKD. In stage 4 CKD, the reduction in GFR is severe, falling below 30 mL/min/1.73 m².

C. Kidney damage with increased GFR:

This interpretation is inaccurate. In stage 4 CKD, kidney damage leads to a progressive decline in GFR, rather than an increase. An increased GFR is not typical of advanced CKD stages; instead, it may occur in conditions such as hyperfiltration in early stages of diabetic nephropathy.

D. Moderately decreased GFR:

This option is also incorrect. Stage 4 CKD is not associated with a moderately decreased GFR. A moderately decreased GFR would typically be indicative of stage 3 CKD, where the GFR ranges from 30 to 59 mL/min/1.73 m². In stage 4 CKD, the reduction in GFR is more severe, falling below 30 mL/min/1.73 m².

A) Small, skin-colored, pedunculated papules in areas of skin folds and on other areas as skin tags:

This description is more characteristic of acrochordons (skin tags), which are benign skin growths often found in skin folds. Skin tags are typically not associated with acne vulgaris.

B) Hyperpigmented areas that vary in form and color and are slightly elevated from the skin:

This description may be indicative of post-inflammatory hyperpigmentation, which can occur after resolution of acne lesions. However, it does not represent the primary pathological findings observed in acne vulgaris.

C) Hyperactive sebaceous areas forming comedones, papules, pustules on the face, neck, and upper back:

Correct. Acne vulgaris is characterized by hyperactive sebaceous glands, leading to the formation of comedones (blackheads and whiteheads), papules, and pustules. These lesions commonly occur on the face, neck, and upper back due to the high density of sebaceous glands in these areas.

D) Sharply demarcated silvery scaling plaques with underlying redness on the elbows and knees:

This description is more indicative of psoriasis, a chronic autoimmune skin condition characterized by silvery scaling plaques and inflammation. Psoriasis typically affects extensor surfaces such as the elbows and knees, rather than the areas commonly affected by acne vulgaris.