After administering sulfonamides to a client, the nurse observes that he has developed a fever, cough, and muscular aches.
The nurse also observes that the client has developed lesions in the form of red wheals on the neck and the mouth.
The nurse interprets these findings as indicating which of the following?

Choice A rationale: Tetracycline can increase the levels of digoxin (Lanoxin) in the blood, leading to an increased risk of digoxin toxicity. This interaction occurs because tetracycline can interfere with the metabolism and excretion of digoxin, causing higher concentrations of the drug in the bloodstream1. Symptoms of digoxin toxicity include nausea, vomiting, dizziness, and cardiac arrhythmias. Therefore, patients taking both medications should be closely monitored for signs of toxicity and may require dosage adjustments.

Choice B rationale: Phenytoin (Dilantin) does not have a significant interaction with tetracycline that increases the risk of toxicity. While both medications can be used together, they do not significantly affect each other's metabolism or excretion1.

Choice C rationale: Vancomycin (Vancocin) does not have a significant interaction with tetracycline that increases the risk of toxicity. Both medications can be used together without causing significant changes in their metabolism or excretion1.

Choice D rationale: Carbamazepine (Tegretol) does not have a significant interaction with tetracycline that increases the risk of toxicity. While both medications can be used together, they do not significantly affect each other's metabolism or excretion

Choice A rationale:

Bloody diarrhea is not typically associated with a fungal superinfection. This symptom is more indicative of gastrointestinal issues and may be related to other causes such as infection or inflammatory bowel disease.

Choice B rationale:

Abdominal cramping is also not a typical sign of a fungal superinfection. It is more likely to be associated with gastrointestinal problems, food intolerances, or other conditions.

Choice D rationale:

Heartburn is not a common sign of a fungal superinfection. It is usually associated with gastroesophageal reflux disease (GERD) or other gastrointestinal issues. Creamy white patches on the throat (Choice C) are indicative of oral thrush, a fungal superinfection. This condition is caused by the overgrowth of Candida albicans and is commonly seen in individuals with compromised immune systems, such as those on immunosuppressive therapy or with HIV. It is important to recognize these white patches as they may require treatment with antifungal medications to prevent further complications.