A nurse is working in a clinical research trial that has a control group and an experimental group but does not know which group is receiving the active drug. Which statement best identifies the research design?

Placebo group

Experimental drug

Control group

Double-blind

Answer and Explanation

The Correct Answer is D

A. Placebo group: A placebo group refers to participants receiving an inactive substance or placebo, not the research design itself.

B. Experimental drug: The term "experimental drug" refers to the drug being tested, not the design of the study.

C. Control group: The control group receives the placebo or standard treatment for comparison, but this term does not describe the study design.

D. Double-blind: A double-blind study is one in which neither the participants nor the researchers know who is receiving the active drug or placebo. This is the correct term for the described scenario.

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Correct Answer is ["A","B"]

Explanation

A. Intramuscular: Intramuscular (IM) injections are absorbed faster than oral medications due to the richer blood supply in muscles compared to subcutaneous tissues.

B. Intravenous: Intravenous (IV) administration provides immediate systemic absorption as the medication is delivered directly into the bloodstream.

C. Topically: Topical medications are applied to the skin and generally have a slower absorption rate compared to systemic routes.

D. Transdermal: Transdermal patches provide a steady, controlled release of medication through the skin, but absorption is slower compared to IM and IV routes.

E. Oral pills: Oral medications are absorbed through the gastrointestinal tract, which is slower compared to IM and IV routes.

A. molecular weight B. fat or liquid solubility C. depth of breathing D. development of a fever E. presence of food

Correct Answer is ["A","B","E"]

Explanation

A. Molecular weight: Drugs with lower molecular weight tend to have higher bioavailability because they can more easily pass through biological membranes.

B. Fat or liquid solubility: Drugs that are fat-soluble can cross cell membranes more easily, affecting their bioavailability. Water-soluble drugs may require transport mechanisms, which can limit absorption.

C. Depth of breathing: The depth of breathing primarily affects the absorption of inhaled drugs, not the general bioavailability of orally or intravenously administered medications.

D. Development of a fever: While fever can affect drug metabolism, it doesn’t directly influence the bioavailability of a drug.

E. Presence of food: Food in the stomach can either enhance or inhibit drug absorption, depending on the drug’s characteristics. This directly impacts bioavailability.

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A nurse is working in a clinical research trial that has a control group and an experimental group but does not know which group is receiving the active drug. Which statement best identifies the research design?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is preparing to administer a medication to a patient. Which routes should the nurse anticipate as leading to quicker systemic absorption? (Select all that apply.)

Correct Answer is ["A","B"]

Explanation

The LPN/LVN is aware that the bioavailability of a drug is based on multiple factors. Which factor(s) would be included? Select all that apply.

Correct Answer is ["A","B","E"]

Explanation

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