A nurse is providing teaching to a client who is receiving intermittent parenteral metronidazole. Which of the following conditions should the nurse recognize as an indication for this medication?

A. The client had a decreased neutrophil count before the medication was administered: This finding may be expected in a client undergoing cytotoxic chemotherapy and receiving filgrastim to stimulate neutrophil production. It is not an indication for an incident report.
B. The client had chemotherapy 12 hr before the medication was administered: The timing of chemotherapy administration is not typically a reason to complete an incident report unless it conflicts with specific medication guidelines or protocols.
C. The vial was out of the refrigerator for 2 hr before the medication was administered:

Filgrastim should be stored in the refrigerator and protected from light. Allowing the medication vial to be out of the refrigerator for an extended period may compromise its stability and effectiveness, potentially leading to adverse effects or reduced efficacy. Therefore, this finding warrants completion of an incident report.
D. The client reported feeling nauseous after the medication was administered: Nausea is a known side effect of filgrastim and is not typically an indication for completing an incident report unless it is severe or persistent and requires intervention.

A. Taking theophylline with coffee may increase its absorption and risk of adverse effects due to caffeine's effects on metabolism, so this statement is not appropriate.
B. Theophylline is a bronchodilator that may cause dehydration as a side effect, so limiting fluid intake is not recommended.
C. Theophylline sustained-release capsules should not be opened, crushed, or chewed, as it can alter the drug's release characteristics and increase the risk of adverse effects.

D. Monitoring blood levels of theophylline is essential to ensure therapeutic effectiveness and avoid toxicity, so the client's understanding of the need for blood level monitoring indicates comprehension of the teaching.