A nurse is providing teaching for a client who has a new prescription for rifampin. Which of the following statements should the nurse include?

The client statement that indicates an understanding of the teaching is: "The medication can cause drowsiness."

Promethazine is an antihistamine medication commonly used to treat various conditions, such as allergies, motion sickness, and nausea. One of the most common side effects of promethazine is drowsiness or sedation. It has a significant sedative effect, and it is often used to induce sleep or manage insomnia in some cases.

Let's go through the other options:

A. "This medication can cause diarrhea": Diarrhea is not a common side effect of promethazine. While promethazine can cause certain gastrointestinal side effects like constipation or upset stomach, diarrhea is not typically associated with its use.

B. "The medication can cause increased salivation": Increased salivation is not a common side effect of promethazine. While some antihistamines can cause dry mouth, which is the opposite of increased salivation, promethazine does not usually cause excessive salivation.

C. "This medication can cause pupil constriction": Pupil constriction (miosis) is a potential side effect of some medications, but it is not commonly associated with promethazine. Promethazine is more likely to cause pupil dilation (mydriasis) rather than constriction.

When caring for a client receiving heparin by continuous IV infusion for the treatment of venous thrombosis, the nurse should monitor the client's aPTT (Activated Partial Thromboplastin Time) to titrate the heparin dose.

Heparin is an anticoagulant medication used to prevent and treat blood clots. The aPTT is a coagulation test that measures the time it takes for the blood to clot when a specific activator is added. Monitoring the aPTT is a standard method for assessing the anticoagulant effect of heparin and ensuring that the client's blood remains within the desired therapeutic range.

The therapeutic range for aPTT while on heparin therapy varies depending on the indication and the client's condition but is generally maintained at a level that prolongs the clotting time enough to prevent and treat thrombosis while avoiding excessive bleeding risk.

Let's go through the other options:

A. Platelet function assay: While monitoring platelet function is essential for assessing overall hemostasis and platelet function, it is not specifically used for titrating heparin doses. Platelet function assays are more commonly used to assess the function of platelets in the context of platelet disorders or antiplatelet medication therapy.

C. INR (International Normalized Ratio): The INR is used to monitor the effect of vitamin K antagonist anticoagulants, such as warfarin, and is not the appropriate test for monitoring heparin therapy.

D. Amylase: Amylase is an enzyme produced by the pancreas and salivary glands and is not relevant for monitoring heparin therapy. Elevated amylase levels are typically associated with pancreatitis and not related to heparin treatment.