A nurse is preparing to administer chlordiazepoxide 50 mg PO every 8 hours to a client. The amount available is chlordiazepoxide 25 mg per capsule. How many capsules should the nurse administer per dose? (Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)

Choice A Reason: This is incorrect because cervical insufficiency is a condition where the cervix dilates prematurely and painlessly during pregnancy, leading to preterm delivery or second trimester abortion. It is not a common cause of first trimester abortion, which occurs before 12 weeks of gestation.

Choice B Reason: This is incorrect because uterine fibroids are benign tumors that grow in or on the uterus. They may cause heavy bleeding, pain, or infertility, but they are not a common cause of first trimester abortion. They may increase the risk of miscarriage in later stages of pregnancy.

Choice C Reason: This is correct because fetal genetic abnormalities are the most common cause of first trimester abortion, accounting for up to 70% of cases. Fetal genetic abnormalities are errors in the number or structure of chromosomes that occur during fertilization or cell division. They can cause developmental defects or fetal demise that result in spontaneous abortion.

Choice D Reason: This is incorrect because maternal disease is not a common cause of first trimester abortion. Maternal disease refers to any medical condition that affects the mother's health or pregnancy outcome, such as diabetes, hypertension, thyroid disorders, or infections. Maternal disease may increase the risk of miscarriage in later stages of pregnancy or cause other complications such as preterm labor or preeclampsia.

Choice A Reason: Nausea is a common presumptive sign of pregnancy, especially in the first trimester. It is caused by hormonal changes and may be accompanied by vomiting.

Choice B Reason: Abdominal enlargement is another presumptive sign of pregnancy, as the uterus grows to accommodate the developing fetus. It may be noticeable as early as 12 weeks of gestation.

Choice C Reason: A positive pregnancy test is a presumptive sign of pregnancy, as it detects the presence of human chorionic gonadotropin (hCG), a hormone produced by the placenta. However, it is not a definitive sign, as it may be affected by other factors such as medications, tumors, or false positives.

Choice D Reason: Braxton Hicks contractions are not a presumptive sign of pregnancy, but a probable sign. They are irregular and painless contractions of the uterus that occur throughout pregnancy, but become more frequent and noticeable in the third trimester. They are also known as false labor contractions.

Choice E Reason: Amenorrhea, or the absence of menstrual periods, is a presumptive sign of pregnancy, as it indicates that ovulation has ceased. However, it is not a definitive sign, as it may be caused by other factors such as stress, illness, or hormonal imbalances.