A nurse is collecting data from a client who is receiving vancomycin for a Clostridium difficile infection.
Which of the following findings is the priority for the nurse to report to the provider?

Choice A rationale:

Increased temperature is not a direct indication of naloxone’s effectiveness. Naloxone works by reversing the effects of opioids, which do not typically include fever.

Choice B rationale:

While naloxone can cause an abrupt withdrawal in opioid-dependent individuals, leading to symptoms such as hypertension, it does not typically decrease blood pressure in opioid overdose cases.

Choice C rationale:

Naloxone works by reversing the life-threatening depression of the central nervous system and respiratory system caused by an opioid overdose. Therefore, an increased respiratory rate after administration would indicate that the medication is effective.

Choice D rationale:

Naloxone reverses the effects of opioids, including pain relief. Therefore, a report of decreased pain would not indicate that the medication is effective.

To solve this problem, we first need to convert the client’s weight from pounds to kilograms. Then, we can calculate the total amount of amikacin needed. Finally, we can find out how many milliliters of amikacin injection the nurse should administer.

1. Convert the client’s weight to kilograms: Given that 1 kg = 2.2 lbs, we can calculate the client’s weight in kilograms as follows:

Weightinkg=WeightinlbsConversionfactor=110lbs2.2lbs/kg≈50kgWeightinkg=ConversionfactorWeightinlbs​=2.2lbs/kg110lbs​≈50kg

1. Calculate the total amount of amikacin needed: The doctor ordered 5 mg of amikacin per kg of body weight, so the total amount of amikacin needed is:

Totalamikacin=Doseperkg×Weightinkg=5mg/kg×50kg=250mgTotalamikacin=Doseperkg×Weightinkg=5mg/kg×50kg=250mg

1. Find out how many milliliters of amikacin injection the nurse should administer: Given that the available amikacin injection is 250 mg/mL, we can calculate the volume of injection needed as follows:

Volumeofinjection=TotalamikacinConcentrationofinjection=250mg250mg/mL=1mLVolumeofinjection=ConcentrationofinjectionTotalamikacin​=250mg/mL250mg​=1mL

So, the nurse should administer 1 mL of amikacin injection.