A nurse is caring for an 18-month-old toddler in the emergency department who has Kawasaki disease. The nurse reviews the toddler's medical record and assessment findings. Which of the following provider prescriptions should the nurse anticipate?

Choice A reason: Intravenous immunoglobulin (IVIG) is the main treatment for Kawasaki disease, as it reduces the inflammation of the blood vessels and the risk of coronary artery aneurysms. IVIG is given as a single infusion over 10 to 12 hours, within the first 10 days of the onset of fever.

Choice B reason: Aspirin is also used to treat Kawasaki disease, as it reduces the fever, pain, and inflammation. However, it is not the first-line treatment, and it is given after IVIG to prevent thrombosis and platelet aggregation. Aspirin is given at a high dose during the acute phase, and then at a low dose until the inflammation subsides.

Choice C reason: Penicillin is not indicated for Kawasaki disease, as it is an antibiotic that treats bacterial infections. Kawasaki disease is not caused by bacteria, but by an unknown trigger that activates the immune system and causes systemic vasculitis.

Choice D reason: Acetaminophen is not effective for Kawasaki disease, as it does not reduce the inflammation or the risk of complications. Acetaminophen may be used to treat mild pain or fever, but it is not the main treatment. Moreover, acetaminophen may mask the fever and delay the diagnosis of Kawasaki disease.

Choice A reason: Gastrointestinal system is not the primary system affected by Kawasaki disease, although some children may have symptoms such as diarrhea, vomiting, or abdominal pain. These are not specific to Kawasaki disease and may be caused by other conditions.

Choice B reason: Cardiovascular system is the most important system to monitor in children with Kawasaki disease, as it can cause inflammation of the blood vessels, especially the coronary arteries that supply the heart. This can lead to serious complications such as coronary artery aneurysms, myocarditis, pericarditis, valvular dysfunction, and arrhythmias. Children with Kawasaki disease need regular echocardiograms to assess the cardiac function and structure.

Choice C reason: Respiratory system is not the primary system affected by Kawasaki disease, although some children may have symptoms such as cough, rhinorrhea, or wheezing. These are not specific to Kawasaki disease and may be caused by other conditions.

Choice D reason: Integumentary system is not the primary system affected by Kawasaki disease, although some children may have symptoms such as rash, peeling of the skin, red eyes, red lips, and red tongue. These are not specific to Kawasaki disease and may be caused by other conditions.