A nurse is caring for a client who is receiving warfarin therapy to prevent deep vein thrombosis. Which of the following medications should the nurse have available in the event of an overdose?
Epinephrine
Vitamin K
Atropine
Protamine
The Correct Answer is B
Choice A reason : Epinephrine is an adrenergic agonist primarily used in the management of cardiac arrest, anaphylaxis, and severe asthma attacks. It is not used to reverse the effects of warfarin overdose. Warfarin acts as an anticoagulant by inhibiting vitamin K-dependent clotting factors, and epinephrine has no role in this mechanism.
Choice B reason : Vitamin K is the antidote for warfarin toxicity. Warfarin works by inhibiting the vitamin K-dependent clotting factors II, VII, IX, and X. In the event of an overdose, vitamin K is administered to reverse the anticoagulant effects of warfarin and restore the clotting factor levels to normal. The administration can be oral or intravenous, depending on the severity of the overdose and the urgency of the situation.
Choice C reason : Atropine is an anticholinergic drug used to treat bradycardia (slow heart rate) and as an antidote for organophosphate poisoning. It does not have a role in reversing warfarin overdose as it does not affect the clotting cascade or vitamin K metabolism.
Choice D reason : Protamine is used to reverse the effects of heparin, another anticoagulant, but not warfarin. Protamine sulfate binds to heparin, forming a stable complex and neutralizing its anticoagulant effects. Since warfarin's mechanism of action is different from heparin's, protamine is not effective in reversing warfarin toxicity.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A reason : In atrial fibrillation, the heartbeat is known to be irregular and often rapid. This irregularity is due to the disorganized electrical signals in the heart's upper chambers, which cause a fast and chaotic heartbeat. Therefore, when documenting the pulse of a client with atrial fibrillation, the term "irregular" is appropriate.
Choice B reason : "Not palpable" would indicate that the pulse cannot be felt, which is not typically the case with atrial fibrillation. While the pulse may be irregular, it is usually still palpable unless the rate is extremely rapid or associated with other complications.
Choice C reason : "Bounding" refers to a pulse that feels strong and full. This is not characteristic of atrial fibrillation. Instead, the pulse in atrial fibrillation may feel weak and irregular due to the ineffective contraction of the atria.
Choice D reason : "Regular" is not an appropriate term to describe the pulse in a client with atrial fibrillation because the condition is characterized by an irregular heart rhythm. The term would be used for a pulse that has consistent beats at regular intervals, which is not the case in atrial fibrillation.
Correct Answer is D
Explanation
Choice A reason : Recently treated bilateral pneumonia is not a contraindication to metoprolol. Metoprolol is a beta-blocker used primarily for the management of hypertension and is not affected by a history of pneumonia.
Choice B reason : While tadalafil is known to interact with medications that lower blood pressure, it is not a direct contraindication to metoprolol. However, caution is advised when they are used concurrently due to the potential for additive blood pressure-lowering effects.
Choice C reason : Diabetes mellitus Type 2, especially when diet-controlled, is not a contraindication to metoprolol. Beta-blockers like metoprolol can mask hypoglycemic symptoms, so patients with diabetes should be monitored closely, but it does not preclude the use of the medication.
Choice D reason : A history of sinus bradycardia is a contraindication to metoprolol. Metoprolol can exacerbate bradycardia, leading to hemodynamic instability and is therefore contraindicated in patients with a history of significant bradycardia.
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