A nurse is caring for a client who has Graves' disease and is to start therapy with propylthiouracil. The nurse should expect which of the following outcomes?

Increased Hct

Decreased WBC count

Decreased heart rate

Increased blood pressure

Answer and Explanation

The Correct Answer is C

A. Increased Hct. Propylthiouracil (PTU) is an antithyroid medication that reduces excessive thyroid hormone production in Graves' disease. It does not directly affect hematocrit (Hct) levels. While anemia can occur in some clients with untreated hyperthyroidism, PTU itself is not expected to raise Hct.

B. Decreased WBC count. A serious adverse effect of PTU is agranulocytosis, which results in a dangerously low white blood cell (WBC) count, increasing the risk of infection. However, this is a potential complication rather than an expected therapeutic outcome. Clients on PTU require regular monitoring of WBC levels to detect early signs of agranulocytosis.

C. Decreased heart rate. Graves’ disease causes hyperthyroidism, which increases metabolism and leads to symptoms such as tachycardia. PTU works by inhibiting thyroid hormone synthesis, leading to a gradual reduction in heart rate as thyroid function normalizes. This is a desired outcome of treatment, helping to reduce cardiovascular strain associated with hyperthyroidism.

D. Increased blood pressure. Hyperthyroidism can cause elevated blood pressure due to increased cardiac output. As PTU lowers thyroid hormone levels, blood pressure is expected to decrease or stabilize rather than increase. An increase in blood pressure would be unexpected and may indicate another underlying issue requiring evaluation.

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Free Nursing Study Resources

Correct Answer is A

Explanation

A. Increase fluid intake. Clients taking lithium should increase fluid intake to 2-3 litres per day to prevent dehydration and maintain proper lithium excretion. Lithium is excreted by the kidneys, and dehydration can lead to toxic accumulation in the body. Adequate hydration also helps reduce the risk of side effects such as nephrotoxicity and lithium-induced polyuria.

B. Decrease sodium intake. Clients should not decrease sodium intake while on lithium. A low-sodium diet increases lithium reabsorption in the kidneys, leading to a higher risk of lithium toxicity. Instead, sodium intake should remain consistent, and clients should avoid excessive sodium restriction or sudden dietary changes.

C. Eat foods high in potassium. Potassium levels are not significantly affected by lithium therapy. While potassium is essential for overall health, increasing potassium intake is not a specific recommendation for lithium users. Potassium-rich foods are more relevant for clients taking diuretics (e.g., furosemide) or cardiac medications like digoxin.

D. Take the medication 1 hr before meals. Lithium is typically taken with food or milk to minimize gastrointestinal irritation. Taking it on an empty stomach can increase the likelihood of nausea and gastric discomfort, making it harder for clients to adhere to treatment. Clients should follow their provider’s instructions regarding meal timing.

A. Levothyroxine B. Cetirizine C. Lithium carbonate D. Albuterol

Correct Answer is C

Explanation

A. Levothyroxine. Levothyroxine is used to treat hypothyroidism and does not have a significant interaction with furosemide. However, both medications require careful monitoring, as hypothyroidism can affect fluid balance, but they are not contraindicated together.

B. Cetirizine. Cetirizine is an antihistamine used to treat allergies and does not interfere with furosemide’s effects. While some antihistamines can cause mild fluid retention, this does not significantly impact furosemide therapy, making them safe to use together.

C. Lithium carbonate. Furosemide is a loop diuretic that increases sodium excretion. Since lithium is excreted through the kidneys in a sodium-dependent manner, a loss of sodium due to diuretic use can lead to reduced lithium excretion and toxic accumulation. Clients taking lithium should avoid diuretics unless absolutely necessary, and their lithium levels must be carefully monitored if diuretics are required.

D. Albuterol. Albuterol is a bronchodilator used for conditions like asthma and COPD. While both furosemide and albuterol can cause hypokalemia, this does not make them absolutely contraindicated. Instead, potassium levels should be regularly monitored, and supplementation may be needed if hypokalemia develops.

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A nurse is caring for a client who has Graves' disease and is to start therapy with propylthiouracil. The nurse should expect which of the following outcomes?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

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Correct Answer is C

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