A nurse is caring for a client who has chronic hepatitis B infection and is taking lamivudine (Epivir).
The nurse should monitor the client for which of the following adverse effects?
Pancreatitis
Lactic acidosis
Hypothyroidism
Nephrotoxicity
The Correct Answer is B
The correct answer is choice B. Lactic acidosis.
Lamivudine (Epivir) is a nucleoside reverse transcriptase inhibitor (NRTI) used to treat chronic hepatitis B infection and HIV infection.
One of the rare but serious adverse effects of lamivudine is lactic acidosis, which is a condition where the blood becomes too acidic due to the accumulation of lactate. Lactic acidosis can cause symptoms such as nausea, vomiting, abdominal pain, muscle weakness, rapid breathing, and low blood pressure.
Choice A is wrong because pancreatitis is not a common side effect of lamivudine.
Pancreatitis is an inflammation of the pancreas that can cause severe abdominal pain, nausea, vomiting, and fever. Pancreatitis is more likely to occur with other NRTIs such as didanosine (Videx) or stavudine (Zerit).
Choice C is wrong because hypothyroidism is not a common side effect of lamivudine.
Hypothyroidism is a condition where the thyroid gland does not produce enough thyroid hormones, which regulate the metabolism and energy levels of the body.
Hypothyroidism can cause symptoms such as fatigue, weight gain, cold intolerance, dry skin, hair loss, and depression.
Hypothyroidism is more likely to occur with other drugs that interfere with thyroid function such as amiodarone (Cordarone) or lithium
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["A","B","C","D","E"]
Explanation
The correct answer is choice A, B, C, D and E.All of these are possible modes of transmission for hepatitis B virus (HBV), which is a viral infection that attacks the liver and can cause both acute and chronic disease.The virus is most commonly transmitted from mother to child during birth and delivery, as well as through contact with blood or other body fluids during sex with an infected partner, unsafe injections or exposures to sharp instruments.
Choice A is correct because unprotected sexual contact can expose a person to the blood, semen, or vaginal fluids of an infected partner.
Choice B is correct because sharing drugs, needles, or “works” when using drugs can expose a person to the blood of an infected person.
Choice C is correct because poor infection control practices in medical settings can expose a person to contaminated needles or syringes or sharp objects that have been used on an infected person.
Choice D is correct because sharing of blood sugar (diabetes) testing equipment can expose a person to the blood of an infected person.
Choice E is correct because needle sticks or sharps exposures on the job can expose a person to the blood of an infected
Correct Answer is A
Explanation
The correct answer is choice A. Bulging fontanelle.
A bulging fontanelle is a sign of increased intracranial pressure, which can be caused by intracranial hemorrhage.
Late-onset VKDB is a condition that occurs in infants who have low levels of vitamin K, which is essential for blood clotting.Most cases of late-onset VKDB present with intracranial hemorrhage.
Choice B. Sunken eyes is wrong because it is a sign of dehydration, not intracranial hemorrhage.
Choice C. Mottled skin is wrong because it is a sign of poor circulation or shock, not intracranial hemorrhage.
Choice D. Flaring nostrils is wrong because it is a sign of respiratory distress, not intracranial hemorrhage.
Normal ranges for vitamin K plasma concentrations are 0.2 to 3.2 ng/mL for adults and 0.15 to 1.5 ng/mL for infants.
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