A nurse is assessing a client who has received oxycodone. The nurse notes that the client's respiratory rate is 8/min. The nurse should identify that which of the following is the pathophysiology for the client's respiratory rate?
Oxycodone inhibits prostaglandin synthesis.
Oxycodone promotes vasodilation of cranial arteries.
Oxycodone blocks the sodium channel suspending nerve conduction.
Oxycodone causes central nervous system depression.
The Correct Answer is D
D) Oxycodone causes central nervous system depression: Oxycodone is an opioid analgesic that acts centrally on the central nervous system (CNS) to relieve pain. One of the most significant side effects of opioids like oxycodone is respiratory depression, which occurs due to the suppression of the CNS, particularly in the brainstem respiratory centers. The brainstem regulates respiratory rate and rhythm, and when opioids depress these centers, it can lead to decreased respiratory drive, resulting in a decrease in respiratory rate. A respiratory rate of 8/min is significantly below the normal range, indicating respiratory depression caused by oxycodone.
A) Oxycodone inhibits prostaglandin synthesis: Oxycodone does not directly inhibit prostaglandin synthesis. Prostaglandins are lipid compounds with various physiological effects, including inflammation and pain modulation. Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, inhibit prostaglandin synthesis by blocking cyclooxygenase enzymes. However, oxycodone primarily acts on opioid receptors in the CNS to relieve pain, rather than through prostaglandin inhibition.
B) Oxycodone promotes vasodilation of cranial arteries: While opioids can cause peripheral vasodilation, particularly in large doses, the primary mechanism of action of oxycodone is not through the promotion of vasodilation of cranial arteries. Vasodilation may occur as a side effect of opioid use, but it is not the primary cause of respiratory depression associated with oxycodone.
C) Oxycodone blocks the sodium channel suspending nerve conduction: This statement describes the mechanism of action of local anesthetics, such as lidocaine, which block sodium channels to inhibit nerve conduction. However, oxycodone is not a sodium channel blocker. Its analgesic effects result from binding to opioid receptors in the CNS, particularly mu-opioid receptors, rather than blocking sodium channels. Therefore, this option is not the pathophysiology for the respiratory rate of 8/min observed in the client receiving oxycodone.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A) Hypertension: Phenelzine is a monoamine oxidase inhibitor (MAOI) used as an antidepressant medication. It works by inhibiting the breakdown of neurotransmitters such as serotonin, norepinephrine, and dopamine in the brain. When phenelzine is taken with foods high in tyramine, such as aged cheese, a potentially dangerous interaction can occur. Tyramine-rich foods can cause the release of stored catecholamines, leading to a sudden increase in blood pressure, known as a hypertensive crisis. Symptoms of a hypertensive crisis can include severe headache, palpitations, chest pain, nausea, vomiting, and sweating. Therefore, hypertension is a manifestation of the interaction between phenelzine and aged cheese.
B) Bradycardia: Bradycardia, or slow heart rate, is not typically associated with the interaction between phenelzine and aged cheese. Instead, the interaction is more commonly associated with a sudden increase in blood pressure (hypertension).
C) Somnolence: Somnolence, or drowsiness, is a common side effect of phenelzine but is not specifically related to the interaction between phenelzine and aged cheese.
D) Diarrhea: Diarrhea is not typically associated with the interaction between phenelzine and aged cheese. Instead, the interaction is more commonly associated with a sudden increase in blood pressure (hypertension).
Correct Answer is B
Explanation
A) Monitor the client's thyroid function levels: This action is not directly relevant to the administration error involving metformin instead of metoprolol. Metformin is not known to affect thyroid function levels. Monitoring thyroid function levels may be appropriate for clients taking certain medications, but it is not indicated in this situation.
B) Check the client's glucose level: Metformin is a medication commonly used to treat type 2 diabetes by lowering blood glucose levels. In this scenario, administering metformin instead of metoprolol could lead to hypoglycemia in the client if they do not have diabetes. Checking the client's glucose level is essential to assess for hypoglycemia and initiate appropriate treatment if necessary.
C) Obtain the client's HDL level: HDL (high-density lipoprotein) level measurement is not directly related to the administration error involving metformin. Metformin is not typically associated with significant effects on HDL levels. Monitoring HDL levels may be relevant for clients with specific cardiovascular risk factors but is not the priority in this situation.
D) Collect the client's uric acid level: Monitoring uric acid levels is not directly relevant to the administration error involving metformin. Metformin is not known to significantly affect uric acid levels. Assessing uric acid levels may be indicated for clients with conditions like gout, but it is not the primary concern in this scenario where the client received the wrong medication.
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