A nurse is administering midazolam (Versed) to a client who is undergoing a colonoscopy. Which of the following actions should the nurse take to prevent respiratory depression?
Administer naloxone (Narcan) before midazolam.
Monitor oxygen saturation and end-tidal CO2 levels.
Give midazolam with food or milk.
Reduce the dose of midazolam by half.
The Correct Answer is B
Monitor oxygen saturation and end-tidal CO2 levels. This is because midazolam (Versed) is a benzodiazepine that can cause respiratory depression and sedation, especially when given intravenously. The nurse should monitor the client’s oxygenation and ventilation status during and after the procedure to prevent hypoxia and hypercapnia.
Choice A is wrong because naloxone (Narcan) is an opioid antagonist that reverses the effects of opioids, not benzodiazepines. Naloxone would not prevent respiratory depression caused by midazolam.
Choice C is wrong because giving midazolam with food or milk would not prevent respiratory depression. Food or milk may delay the absorption of oral midazolam, but it would not affect the intravenous administration.
Choice D is wrong because reducing the dose of midazolam by half may not be sufficient to prevent respiratory depression. The dose of midazolam should be individualized based on the client’s age, weight, health status, and response to the drug. Reducing the dose by half may also compromise the quality of sedation and analgesia during the colonoscopy.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Buspirone (BuSpar) is an anxiolytic medication that works by binding to serotonin and dopamine receptors in the brain, which helps regulate mood and reduce anxiety.
Choice B is wrong because it describes the mechanism of action of benzodiazepines, such as lorazepam or diazepam, which enhance the activity of GABA, a neurotransmitter that inhibits anxiety and arousal.
Choice C is wrong because it describes the mechanism of action of selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine or sertraline, which block the reuptake of serotonin, a neurotransmitter that influences mood and anxiety.
Choice D is wrong because it describes the mechanism of action of monoamine oxidase inhibitors (MAOIs), such as phenelzine or tranylcypromine, which inhibit the breakdown of norepinephrine, a neurotransmitter that affects alertness and energy.
Correct Answer is C
Explanation
Ketoconazole (Nizoral) can interact with zolpidem (Ambien) and increase its sedative effects.Ketoconazole is an antifungal medication that inhibits the metabolism of zolpidem, leading to higher plasma levels and increased risk of adverse effects such as drowsiness, dizziness, and impaired coordination.
Choice A is wrong because omeprazole (Prilosec) is a proton pump inhibitor that does not affect the metabolism or clearance of zolpidem.
Choice B is wrong because warfarin (Coumadin) is an anticoagulant that does not interact with zolpidem.However, warfarin levels may be affected by other medications or dietary factors that influence clotting.
Choice D is wrong because metformin (Glucophage) is an antidiabetic medication that does not interact with zolpidem.Metformin may cause gastrointestinal side effects such as nausea, diarrhea, and abdominal pain, but these are not related to zolpidem use.
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