A nurse is administering midazolam (Versed) to a client who is undergoing a colonoscopy. Which of the following actions should the nurse take to prevent respiratory depression?

Buspirone (BuSpar) is an anxiolytic medication that works by binding to serotonin and dopamine receptors in the brain, which helps regulate mood and reduce anxiety.

Choice B is wrong because it describes the mechanism of action of benzodiazepines, such as lorazepam or diazepam, which enhance the activity of GABA, a neurotransmitter that inhibits anxiety and arousal.

Choice C is wrong because it describes the mechanism of action of selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine or sertraline, which block the reuptake of serotonin, a neurotransmitter that influences mood and anxiety.

Choice D is wrong because it describes the mechanism of action of monoamine oxidase inhibitors (MAOIs), such as phenelzine or tranylcypromine, which inhibit the breakdown of norepinephrine, a neurotransmitter that affects alertness and energy.

Monitor oxygen saturation and end-tidal CO2 levels.This is because midazolam (Versed) is a benzodiazepine that can cause respiratory depression and sedation, especially when given intravenously. The nurse should monitor the client’s oxygenation and ventilation status during and after the procedure to prevent hypoxia and hypercapnia.

Choice A is wrong because naloxone (Narcan) is an opioid antagonist that reverses the effects of opioids, not benzodiazepines.Naloxone would not prevent respiratory depression caused by midazolam.

Choice C is wrong because giving midazolam with food or milk would not prevent respiratory depression.Food or milk may delay the absorption of oral midazolam, but it would not affect the intravenous administration.

Choice D is wrong because reducing the dose of midazolam by half may not be sufficient to prevent respiratory depression.The dose of midazolam should be individualized based on the client’s age, weight, health status, and response to the drug. Reducing the dose by half may also compromise the quality of sedation and analgesia during the colonoscopy.