A nurse is reviewing the medication history of a client who is prescribed zolpidem (Ambien) for insomnia. The nurse should identify that which of the following medications can interact with zolpidem and increase its sedative effects?
Omeprazole (Prilosec)
Warfarin (Coumadin)
Ketoconazole (Nizoral)
Metformin (Glucophage)
The Correct Answer is C
Ketoconazole (Nizoral) can interact with zolpidem (Ambien) and increase its sedative effects. Ketoconazole is an antifungal medication that inhibits the metabolism of zolpidem, leading to higher plasma levels and increased risk of adverse effects such as drowsiness, dizziness, and impaired coordination.
Choice A is wrong because omeprazole (Prilosec) is a proton pump inhibitor that does not affect the metabolism or clearance of zolpidem.
Choice B is wrong because warfarin (Coumadin) is an anticoagulant that does not interact with zolpidem. However, warfarin levels may be affected by other medications or dietary factors that influence clotting.
Choice D is wrong because metformin (Glucophage) is an antidiabetic medication that does not interact with zolpidem. Metformin may cause gastrointestinal side effects such as nausea, diarrhea, and abdominal pain, but these are not related to zolpidem use.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Ketoconazole (Nizoral) can interact with zolpidem (Ambien) and increase its sedative effects.Ketoconazole is an antifungal medication that inhibits the metabolism of zolpidem, leading to higher plasma levels and increased risk of adverse effects such as drowsiness, dizziness, and impaired coordination.
Choice A is wrong because omeprazole (Prilosec) is a proton pump inhibitor that does not affect the metabolism or clearance of zolpidem.
Choice B is wrong because warfarin (Coumadin) is an anticoagulant that does not interact with zolpidem.However, warfarin levels may be affected by other medications or dietary factors that influence clotting.
Choice D is wrong because metformin (Glucophage) is an antidiabetic medication that does not interact with zolpidem.Metformin may cause gastrointestinal side effects such as nausea, diarrhea, and abdominal pain, but these are not related to zolpidem use.
Correct Answer is ["A","B","C","E"]
Explanation
The nurse should monitor the client’s blood pressure, respiratory rate, liver function tests and mental status because chlordiazepoxide (Librium) is a benzodiazepine that can cause respiratory depression, hypotension, hepatic impairment and sedation.The nurse should also monitor for signs of withdrawal such as anxiety, tremors, seizures and delirium.
Choice D is wrong because blood glucose level is not affected by chlordiazepoxide or alcohol withdrawal.Blood glucose level is more relevant for clients who have diabetes or are taking medications that alter glucose metabolism.
Normal ranges for blood pressure are 90/60 mmHg to 120/80 mmHg, for respiratory rate are 12 to 20 breaths per minute, for liver function tests are AST 10 to 40 U/L, ALT 7 to 56 U/L, ALP 45 to 115 U/L, bilirubin 0.1 to 1.2 mg/dL and for mental status are alert and oriented to person, place, time and situation.
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