A nurse in a pediatric clinic is discussing the pathophysiology of Reye syndrome with a newly licensed nurse. Which of the following statements by the newly licensed nurse indicate an understanding of the disorder?
"Reye syndrome causes fatty changes in the liver."
"Reye syndrome leads to venous thrombus formation."
"Reye syndrome is associated with misuse of acetaminophen."
"Reye syndrome is linked to decreased serum ammonia levels."
The Correct Answer is A
A. "Reye syndrome causes fatty changes in the liver."
This statement is correct. Reye syndrome is characterized by acute non-inflammatory encephalopathy and fatty changes in the liver, which can lead to liver dysfunction and failure.
B. "Reye syndrome leads to venous thrombus formation."
This statement is incorrect. Reye syndrome primarily affects the brain and liver, leading to cerebral edema and liver dysfunction. It does not typically involve venous thrombus formation.
C. "Reye syndrome is associated with misuse of acetaminophen."
This statement is incorrect. While the exact cause of Reye syndrome is not fully understood, it is not associated with the misuse of acetaminophen. However, there is a well-established association between Reye syndrome and the use of aspirin (salicylates) during viral infections, particularly in children and adolescents.
D. "Reye syndrome is linked to decreased serum ammonia levels."
This statement is incorrect. Reye syndrome is associated with increased serum ammonia levels due to liver dysfunction and impaired ammonia metabolism. Elevated ammonia levels can contribute to the encephalopathy seen in Reye syndrome.

Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["C","E"]
Explanation
A. "Hyperextend your child's head for 5 minutes following a seizure."
This instruction is incorrect. Hyperextending the head after a seizure is not recommended and could potentially cause harm. Instead, it's important to ensure that the child's airway is clear and maintain a safe and comfortable position.
B. "Immediately following a seizure, give your child 6 ounces of water."
This instruction is not necessary unless the child specifically requests water or appears to be dehydrated. It's important to focus on ensuring the child's safety and comfort immediately after a seizure.
C. "Following a seizure, record the length and characteristics of your child's seizure."
This instruction is correct. Keeping a record of the length and characteristics of the child's seizures can provide valuable information to healthcare providers for managing the child's epilepsy and adjusting treatment as needed.
D. "Administer rectal diazepam to your child following a seizure."
This instruction may be appropriate in some cases, particularly if the child's seizures are prolonged or if they have a history of status epilepticus. However, the administration of rectal diazepam should be done according to the healthcare provider's instructions and with proper training.
E. "Call for emergency medical services if the size of your child's pupils are unequal after a seizure."
This instruction is correct. Unequal pupil size (anisocoria) after a seizure could indicate a serious underlying condition and should prompt immediate medical evaluation. It's important for the parents to be aware of this potential sign of concern and to seek prompt medical attention if it occurs.
Correct Answer is D
Explanation
A. Dry mouth: Dry mouth is not a common adverse effect of cefazolin. It is more commonly associated with other medications, such as anticholinergic drugs. While dry mouth may be uncomfortable, it is not typically considered a serious adverse effect of cefazolin that requires immediate reporting.
B. Constipation: Constipation is also not a common adverse effect of cefazolin. It is more commonly associated with other medications, dietary factors, or underlying medical conditions. Similar to dry mouth, constipation is not typically considered a serious adverse effect of cefazolin that requires immediate reporting.
C. Back pain: Back pain is not a common adverse effect of cefazolin. While musculoskeletal adverse effects can occur with some antibiotics, back pain is not typically associated with cefazolin. However, if severe or persistent back pain occurs, it should be reported to the healthcare provider for evaluation.
D. Urticaria: Urticaria, also known as hives, is a potential adverse effect of cefazolin and other antibiotics. It is characterized by raised, itchy welts on the skin and can be a sign of an allergic reaction. Urticaria should be reported to the healthcare provider immediately, as it may indicate a serious allergic reaction requiring prompt medical attention.
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