A nurse in a clinic is reviewing the laboratory values of a patient who has primary hypothyroidism. The nurse should anticipate an elevation in which of the following laboratory values?

Choice A rationale
Fever is not a typical symptom of osteoarthritis of the knee. Osteoarthritis is a degenerative joint disease that causes pain and stiffness, but it does not typically cause systemic symptoms like fever.
Choice B rationale
This is the correct answer. Crepitus, which is a grating or crackling sound or sensation, can be a symptom of osteoarthritis of the knee. It is caused by the rubbing of bone on bone due to the loss of protective cartilage in the joint.
Choice C rationale
Malaise, or a general feeling of discomfort or illness, is not a specific symptom of osteoarthritis of the knee. While osteoarthritis can cause discomfort and limit activity, it does not typically cause generalized malaise.
Choice D rationale
Weakness can occur in the muscles around an affected joint due to lack of use or muscle atrophy, but it is not a primary symptom of osteoarthritis of the knee

Choice A rationale
The effectiveness of pancreatic enzyme replacement therapy in patients with chronic pancreatitis can be evaluated by observing the patient’s stool. Pancreatic enzyme replacement therapy (PERT) is used to improve digestion and absorption of nutrients in patients with pancreatic insufficiency, a common complication of chronic pancreatitis. One of the primary goals of PERT is to reduce steatorrhea, or fatty stools, which is a common symptom of pancreatic insufficiency. Therefore, observing changes in the patient’s stool, such as a reduction in fat content, can help evaluate the effectiveness of PERT567.
Choice B rationale
While saliva plays a role in the initial stages of digestion, it is not typically used to evaluate the effectiveness of pancreatic enzyme replacement therapy in patients with chronic pancreatitis. PERT is primarily aimed at improving the digestion and absorption of nutrients in the intestines, and changes in saliva are not indicative of the effectiveness of this therapy.
Choice C rationale
Nasal mucus is not typically used to evaluate the effectiveness of pancreatic enzyme replacement therapy in patients with chronic pancreatitis. PERT is primarily aimed at improving the digestion and absorption of nutrients in the intestines, and changes in nasal mucus are not indicative of the effectiveness of this therapy.
Choice D rationale
Urine is not typically used to evaluate the effectiveness of pancreatic enzyme replacement therapy in patients with chronic pancreatitis. PERT is primarily aimed at improving the digestion and absorption of nutrients in the intestines, and changes in urine are not indicative of the effectiveness of this therapy.