A client is prescribed lisinopril 20 mg PO daily for the treatment of hypertension. Which finding would alert the nurse that a side effect of the medication has occurred?

Choice A Reason
Ceftriaxone is an antibiotic that may be prescribed during COPD exacerbations to treat or prevent infection. A white blood cell count of 16,000 u/L indicates an elevated level, which could be a response to infection. Therefore, ceftriaxone would be appropriate, and there is no need to question this medication based on the white blood cell count.

Choice B Reason
Zafirlukast is a leukotriene receptor antagonist used for the prophylactic treatment of asthma, and it may be used off-label for COPD. AST and ALT levels are liver enzymes, and the values provided (AST of 30 units/L and ALT of 20 units/L) are within normal ranges. Thus, there is no immediate concern regarding liver function that would prompt the nurse to question the use of zafirlukast.

Choice C Reason
Theophylline is a bronchodilator used in the treatment of COPD. However, a theophylline level of 21 mg/dL is above the therapeutic range, which is generally considered to be 5-15 mg/dL. Levels above 20 mg/dL are associated with toxicity and can lead to serious side effects such as seizures or arrhythmias. Therefore, the nurse should question this medication due to the high theophylline level.

Choice D Reason
Prednisone is a corticosteroid that may be used to reduce inflammation during COPD exacerbations. A glucose level of 110 mg/dL is slightly elevated but may be expected as corticosteroids can increase blood sugar levels. This would not typically be a reason to question the use of prednisone unless the patient has poorly controlled diabetes or other specific contraindications.

Choice A Reason:
Autism Spectrum Disorder (ASD) is characterized by challenges with social skills, repetitive behaviors, and communication difficulties. Jaw clenching and rocking are forms of self-stimulatory behavior (stimming) often observed in individuals with ASD¹³¹⁴. These behaviors can serve as a coping mechanism to manage sensory overload or express emotions.

Choice B Reason:
Stereotypic Movement Disorder involves repetitive, seemingly purposeless movements. While jaw clenching and rocking could be symptoms, they are more commonly associated with ASD. Stereotypic Movement Disorder is typically diagnosed when these behaviors interfere significantly with normal activities or result in self-harm, which is not mentioned in the child's description.

Choice C Reason:
Attention Deficit Hyperactivity Disorder (ADHD) is marked by an ongoing pattern of inattention and/or hyperactivity-impulsivity that interferes with functioning or development. The behaviors described, jaw clenching and rocking, are not typical indicators of ADHD, which more commonly includes symptoms like difficulty staying focused, hyperactivity, and impulsive actions.

Choice D Reason:
Intellectual Disability Disorder is characterized by limitations in intellectual functioning and adaptive behavior, which covers a range of everyday social and practical skills. The behaviors of jaw clenching and rocking do not directly indicate Intellectual Disability Disorder. This condition is usually identified by deficits in intellectual and adaptive functioning, not by specific behaviors like those described.