A client has been diagnosed with hypothyroidism. What information should the nurse obtain when conducting a focused assessment? Select all that apply.

Choice A Reason: Parkinson's disease does not result from too low acetylcholine as a result of an autoimmune reaction, but this may be a description of myasthenia gravis, which affects the neuromuscular junction.

Choice B Reason: Parkinson's disease is not caused by the deterioration of the myelin sheath of the basal ganglia, but this may be a description of multiple sclerosis, which affects the central nervous system.

Choice C Reason: Excess dopamine and deficient acetylcholine are not the two major causes of Parkinson's disease, but they are reversed. Parkinson's disease is caused by low dopamine and high acetylcholine levels in the brain.

Choice D Reason: Parkinson's is caused by depletion of dopamine and excess of acetylcholine, as this affects the balance between these two neurotransmitters that control movement and coordination.

Choice A Reason: Swollen, painful joints are not a sign of Lyme disease in the early stage, but they may occur in the late stage, which can take months or years to develop.

Choice B Reason: An expanding circular rash, also known as erythema migrans, is a sign of Lyme disease in the early stage, which usually appears within 3 to 30 days after the tick bite. The rash may have a bull's-eye appearance and can spread up to 12 inches in diameter.

Choice C Reason: Decreased level of consciousness is not a sign of Lyme disease, but it may indicate other serious conditions such as meningitis, encephalitis, or stroke.

Choice D Reason: Necrosis at the site of the bite is not a sign of Lyme disease, but it may indicate a brown recluse spider bite, which can cause tissue damage and ulceration.