A 55-year-old patient with rheumatoid arthritis is being evaluated for disease progression. Which of the following laboratory findings is most indicative of increased disease activity?
Presence of anti-cyclic citrullinated peptide (anti-CCP) antibodies
Elevated rheumatoid factor (RF) levels
Decreased erythrocyte sedimentation rate (ESR)
Elevated C-reactive protein (CRP) levels
The Correct Answer is D
A. Anti-cyclic citrullinated peptide (anti-CCP) antibodies are specific for rheumatoid arthritis but are not necessarily linked to disease activity.
B. Elevated rheumatoid factor (RF) levels are common in rheumatoid arthritis but not always indicative of disease activity.
C. A decreased erythrocyte sedimentation rate (ESR) is typically a sign of less inflammation, not more.
D. Elevated C-reactive protein (CRP) levels are a direct marker of inflammation and are often correlated with increased disease activity in rheumatoid arthritis.
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Related Questions
Correct Answer is B
Explanation
A. Almond milk can be a good source of calcium, but it is often lower in calcium compared to dairy products unless fortified.
B. Low-fat milk is an excellent source of calcium and is also easy for most people to digest.
C. Whole milk contains calcium, but it is higher in fat, which is not ideal for individuals at risk for osteoporosis.
D. Soy milk can be a good source of calcium if fortified, but it does not always contain as much calcium as low-fat milk.
Correct Answer is ["A","C","E"]
Explanation
A. Hirsutism (excessive hair growth) can occur due to corticosteroid use, as they can increase the production of androgens.
B. Bladder spasms are not typically associated with corticosteroid use but may occur with multiple sclerosis itself.
C. Hyperglycemia is a common side effect of corticosteroids, as they can impair insulin sensitivity.
D. Corticosteroids typically cause hypertension, not hypotension, as a side effect.
E. Delayed wound healing is a well-known side effect of corticosteroid therapy, as steroids can suppress immune function.
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