A 40-year-old patient with polycystic kidney disease is scheduled to receive a kidney transplant.
When the nurse begins to administer 2 units of leukocyte-poor packed red blood cells to treat a low hemoglobin level, the patient asks why this has been prescribed.
What is the appropriate response from the nurse?
“It will reduce the risk of receiving white blood cells from the donor that could impair the function of your transplanted kidney.”
“All pre-transplant patients receive leukocyte-poor blood because it is better absorbed by the body.”
“It causes fewer blood reactions in pre-transplant patients.”
“It is less likely to cause hemolysis, or destruction of the blood cells, after transfusion.”
The Correct Answer is A
Choice A rationale:
Leukocyte-poor packed red blood cells (LP-PRBCs) have a significantly reduced number of white blood cells (WBCs), also known as leukocytes. This is crucial for pre-transplant patients like the one in the question for several reasons:
Prevention of Alloimmunization: WBCs in blood transfusions carry human leukocyte antigens (HLAs), which are proteins on the surface of cells that play a role in the immune system. Exposure to foreign HLAs can cause the recipient's immune system to develop antibodies against them, a process called alloimmunization. These antibodies can then attack and damage the transplanted kidney, leading to rejection. By reducing the number of WBCs in the transfusion, LP-PRBCs significantly lower the risk of alloimmunization.
Reduced Incidence of Febrile Non-Hemolytic Transfusion Reactions (FNHTRs): FNHTRs are the most common type of transfusion reaction, characterized by fever, chills, and occasionally other symptoms like nausea and vomiting. They are thought to be caused by cytokines released from WBCs in the transfused blood. LP-PRBCs, with their reduced WBC content, have been shown to lower the incidence of FNHTRs.
Potential Benefits for Graft Survival: Some studies have suggested that the use of LP-PRBCs for transfusions may improve long-term graft survival rates in kidney transplant patients, although more research is needed to confirm these findings.
Choice B rationale:
This statement is incorrect. While LP-PRBCs may have some advantages in terms of absorption or utilization, this is not the primary reason for their use in pre-transplant patients. The main goal is to reduce the risk of alloimmunization and other transfusion-related complications.
Choice C rationale:
This statement is partially correct. LP-PRBCs do tend to cause fewer blood reactions, particularly FNHTRs, as explained in the rationale for Choice A. However, this is not the most comprehensive or accurate explanation for their use in pre-transplant patients.
Choice D rationale:
This statement is not directly relevant to the use of LP-PRBCs in pre-transplant patients. While LP-PRBCs may have a lower risk of hemolysis, this is not the primary reason for their use in this specific context.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A rationale:
While working in a facility affiliated with a medical or nursing school can offer opportunities for professional development and collaboration, it is not the most important factor to consider when choosing a new job.
Affiliation with a school does not guarantee a positive work environment, strong nursing leadership, or a commitment to quality patient care, which are all hallmarks of Magnet hospitals.
It's essential to consider other factors that directly impact job satisfaction, patient outcomes, and overall nursing excellence.
Choice B rationale:
Having the latest technology can be beneficial, but it does not ensure a supportive work environment or a high standard of nursing care.
Technology is only one aspect of a hospital's operations, and it should not be the primary focus when making a career decision. It's crucial to prioritize factors that directly influence the quality of nursing practice and patient outcomes.
Choice C rationale:
Inquiring about nurse-client ratios is important, as it can provide insight into the workload and staffing levels at a hospital. However, it's not the most comprehensive indicator of a hospital's commitment to nursing excellence.
Magnet status, in contrast, signifies a broader commitment to quality nursing care, professional development, and positive work environments.
Choice D rationale:
Magnet status is a prestigious designation awarded by the American Nurses Credentialing Center (ANCC) to hospitals that demonstrate excellence in nursing care, leadership, and innovation.
Magnet hospitals are known for:
Attracting and retaining highly qualified nurses Fostering a culture of collaboration and teamwork Investing in professional development and growth
Promoting evidence-based practice and quality improvement Demonstrating outstanding patient outcomes
Seeking employment at a Magnet hospital is strongly recommended for nurses who prioritize professional growth, job satisfaction, and the delivery of exceptional patient care.
Correct Answer is B
Explanation
Choice A rationale:
Explaining legal requirements to inform sex partners at this initial stage is not the most appropriate or supportive intervention.
The client is in a state of emotional distress and may not be receptive to information about legal obligations. It's crucial to first address the client's emotional needs and provide support before discussing legal matters.
Prematurely focusing on legalities could further overwhelm the client and potentially hinder the development of a trusting relationship with the nurse.
Choice C rationale:
Offering to inform the family for the client, while well-intentioned, may not respect the client's autonomy and right to privacy. The decision to disclose HIV status to family members is a personal one that should be made by the client, not the nurse.
It's important to empower the client to make their own choices about disclosure and provide support throughout the process.
Choice D rationale:
Determining if a clergy member would help could be a valuable resource for some clients, but it should not be the first or only intervention.
It's essential to first assess the client's individual needs and preferences regarding spiritual support.
Not all clients may find comfort in religious or spiritual guidance, and some may prefer to seek support from other sources.
Choice B rationale:
Assessing the client for support systems is the most appropriate initial intervention because it focuses on the client's immediate needs for emotional support and connection.
By identifying existing support systems (such as family, friends, or community organizations), the nurse can help the client access resources that can provide comfort, understanding, and assistance in coping with the diagnosis.
This approach recognizes the client's emotional state and prioritizes their psychosocial well-being, which is essential in the initial stages of coping with an HIV diagnosis.
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